Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.56 |
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.51 |
| ▸ | GCGR | P47871 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14407423 | 0.93 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL10910380 | 0.93 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL6958523 | 0.93 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL19864312 | 0.86 | MAPK14 (0.73) | NPC1RAB9ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL19626569 | 0.82 | MAPK13 (0.61) | NPC1RAB9ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL9568857 | 0.80 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL762311 | 0.79 | NR4A2 (0.62) | NPC1RAB9ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL25351821 | 0.78 | NR4A2 (0.67) | NPC1RAB9ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL11752484 | 0.78 | RXRA (0.46) | NPC1RAB9ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL11755115 | 0.78 | RXRA (0.46) | NPC1RAB9ASMN1; SMN2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358016-B2 | Electrophotographic photoreceptor and electrophoto-graphic apparatus equipped with the same | OSAKA GAS CO., LTD. (JP) | 2008-04-15 | — | — | US | disclosed |
| US-7358016-B2 | Electrophotographic photoreceptor and electrophoto-graphic apparatus equipped with the same | OSAKA GAS CO., LTD. (JP) | 2008-04-15 | — | — | US | disclosed |