Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.30 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.30 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.30 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | TOP2A | P11388 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4846358 | 0.77 | EIF2AK2 (0.53) | DHFRMAPK13EIF2AK2MAPK12MAPK11 | |
| SCHEMBL12083845 | 0.64 | LRRK2 (0.55) | LRRK2 | |
| SCHEMBL4850756 | 0.56 | POLB (0.43) | DHFR | |
| SCHEMBL4850760 | 0.56 | POLB (0.43) | DHFR | |
| SCHEMBL4814026 | 0.55 | DHFR (0.47) | DHFR | |
| SCHEMBL14196855 | 0.55 | USP2 (0.42) | DHFR | |
| SCHEMBL4823145 | 0.55 | CYP1A2 (0.48) | DHFR | |
| SCHEMBL4820619 | 0.55 | CYP1A2 (0.48) | DHFR | |
| SCHEMBL11120339 | 0.54 | EIF2AK2 (0.62) | MAPK13EIF2AK2MAPK12MAPK11MAPK14 | |
| SCHEMBL15380522 | 0.54 | DHFR (0.79) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7364825-B2 | Charge transport materials having a nitrogen-containing-heterocycle hydrazone group | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-04-29 | — | — | US | disclosed |
| US-7364825-B2 | Charge transport materials having a nitrogen-containing-heterocycle hydrazone group | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-04-29 | — | — | US | disclosed |