Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK2 | P19525 | 2/20 | 0.53 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.53 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.53 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 10/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8176664 | 0.78 | EIF2AK2 (0.66) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL14196859 | 0.77 | LRRK2 (0.34) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL11120339 | 0.76 | EIF2AK2 (0.62) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL30821077 | 0.70 | EIF2AK2 (0.67) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL8171875 | 0.70 | EIF2AK2 (1.00) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL8172006 | 0.70 | EIF2AK2 (0.54) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL10349467 | 0.66 | EIF2AK2 (0.56) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL13147782 | 0.64 | EIF2AK2 (0.50) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL9286184 | 0.64 | EIF2AK2 (0.53) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL10920505 | 0.64 | DHFR (0.66) | DHFRHTTL3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7364825-B2 | Charge transport materials having a nitrogen-containing-heterocycle hydrazone group | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-04-29 | — | — | US | disclosed |
| US-20060177750-A1 | Charge transport materials having a nitrogen-containing-heterocycle hydrazone group | S-PRINTING SOLUTION CO., LTD. (KR) | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060177750-A1 | Charge transport materials having a nitrogen-containing-heterocycle hydrazone group | SLC1A2, SLC9B2, SLC6A19 | EIF2AK2 4482/4885MAPK12 2969/4885MAPK13 2936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.