SCHEMBL14196868

SCHEMBL14196868

CN(/N=C/c1ccc2c(c1)c1ccccc1n2C)c1ccc(S(C)(=O)=O)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.43
POLB P06746 6/20 0.43
MEN1 O00255 6/20 0.43
RAB9A P51151 3/20 0.43
APOBEC3A P31941 1/20 0.43
APOBEC3G Q9HC16 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CASP6 P55212 1/20 0.41
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41
MAPT P10636 4/20 0.40
GAA P10253 1/20 0.39
PSEN1 P49768 1/20 0.39
PSEN2 P49810 1/20 0.39
APH1B Q8WW43 1/20 0.39
NCSTN Q92542 1/20 0.39
APH1A Q96BI3 1/20 0.39
PSENEN Q9NZ42 1/20 0.39
KDM4E B2RXH2 3/20 0.39
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9815537 0.86 KMT2A (0.50) KMT2APOLBMEN1RAB9AAPOBEC3A
SCHEMBL16900542 0.84 POLB (0.56) KMT2APOLBMEN1RAB9AAPOBEC3A
SCHEMBL14196943 0.79 KMT2A (0.52) KMT2APOLBMEN1RAB9AAPOBEC3A
SCHEMBL1335846 0.74 KMT2A (0.48) KMT2APOLBMEN1RAB9AAPOBEC3A
SCHEMBL1335849 0.74 KMT2A (0.48) KMT2APOLBMEN1RAB9AAPOBEC3A
SCHEMBL13219228 0.74 KMT2A (0.48) KMT2APOLBMEN1RAB9AAPOBEC3A
SCHEMBL14224628 0.74 KDM4E (0.52) KMT2APOLBMEN1RAB9ATDP1
SCHEMBL17427783 0.74 POLB (0.46) KMT2APOLBMEN1RAB9AAPOBEC3A
SCHEMBL128424 0.73 KDM4E (0.64) KMT2APOLBMEN1RAB9ATDP1
SCHEMBL1596345 0.73 KDM4E (0.64) KMT2APOLBMEN1RAB9ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7358014-B2 Electrophotographic organophotoreceptors with novel charge transport compounds SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-04-15 US disclosed