Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 9/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | DTYMK | P23919 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4505573 | 0.90 | L3MBTL1 (0.39) | L3MBTL1BRD4ELANEATMDTYMK | |
| SCHEMBL30940044 | 0.79 | L3MBTL1 (0.47) | L3MBTL1BRD4ELANEDTYMKHTR6 | |
| SCHEMBL4569771 | 0.79 | L3MBTL1 (0.50) | L3MBTL1BRD4ELANEDTYMKHTR6 | |
| SCHEMBL3705482 | 0.79 | L3MBTL1 (0.47) | L3MBTL1BRD4ELANEDTYMKHTR6 | |
| SCHEMBL22978451 | 0.79 | L3MBTL1 (0.41) | L3MBTL1BRD4ELANEATMDTYMK | |
| SCHEMBL30458558 | 0.77 | ELANE (0.46) | L3MBTL1BRD4ELANEDTYMKHTR6 | |
| SCHEMBL1267232 | 0.77 | ELANE (0.46) | L3MBTL1BRD4ELANEDTYMKHTR6 | |
| SCHEMBL4572234 | 0.77 | L3MBTL1 (0.46) | L3MBTL1BRD4ELANEDTYMKHTR6 | |
| SCHEMBL22978450 | 0.76 | ELANE (0.39) | L3MBTL1BRD4ELANEDTYMKPOLB | |
| SCHEMBL295518 | 0.75 | ELANE (0.55) | L3MBTL1ELANEDTYMKDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064265-A2 | COMPOUNDS MODULATING C-FMS AND/OR C-KIT ACTIVITY AND USES THEREFOR | PLEXXIKON, INC. (US) | 2008-05-29 | — | — | WO | disclosed |