Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DTYMK | P23919 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28466951 | 0.87 | ELANE (0.41) | ELANEPOLBMITFPKMBRD4 | |
| SCHEMBL22978451 | 0.84 | L3MBTL1 (0.41) | ELANEL3MBTL1POLBBRD4DTYMK | |
| SCHEMBL4505573 | 0.77 | L3MBTL1 (0.39) | ELANEL3MBTL1BRD4CYP2C19DTYMK | |
| SCHEMBL3705482 | 0.77 | L3MBTL1 (0.47) | ELANEL3MBTL1POLBBRD4DTYMK | |
| SCHEMBL30940044 | 0.77 | L3MBTL1 (0.47) | ELANEL3MBTL1POLBBRD4DTYMK | |
| SCHEMBL4569771 | 0.77 | L3MBTL1 (0.50) | ELANEL3MBTL1POLBBRD4DTYMK | |
| SCHEMBL22988825 | 0.76 | CSF1R (0.44) | ELANEL3MBTL1DTYMK | |
| SCHEMBL14197023 | 0.76 | L3MBTL1 (0.38) | ELANEL3MBTL1POLBBRD4DTYMK | |
| SCHEMBL30458558 | 0.75 | ELANE (0.46) | ELANEL3MBTL1POLBBRD4DTYMK | |
| SCHEMBL1267232 | 0.75 | ELANE (0.46) | ELANEL3MBTL1POLBBRD4DTYMK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018233526-A9 | CSF1R INHIBITOR, AND MANUFACTURING METHOD THEREFOR AND APPLICATION THEREOF | 上海和誉生物医药科技有限公司 | 2021-02-18 | — | — | WO | disclosed |