Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.32 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.32 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.32 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14197172 | 0.88 | LMNA (0.40) | PDE10AKDM4EPOLBLMNAL3MBTL1 | |
| SCHEMBL14196304 | 0.84 | PDE10A (0.34) | IRAK4PDE10AKDM4EPOLBFYN | |
| SCHEMBL14197179 | 0.83 | ADORA1 (0.36) | L3MBTL1 | |
| SCHEMBL14196672 | 0.83 | IRAK4 (0.33) | IRAK4PDE10AKDM4EPOLBL3MBTL1 | |
| SCHEMBL14196014 | 0.82 | JAK3 (0.33) | IRAK4PDE10A | |
| SCHEMBL14196447 | 0.82 | IRAK4 (0.41) | IRAK4 | |
| SCHEMBL14196024 | 0.81 | USP30 (0.35) | IRAK4PDE10AKDM4ELMNAL3MBTL1 | |
| SCHEMBL14197165 | 0.81 | EPHX1 (0.39) | IRAK4PDE10A | |
| SCHEMBL14197163 | 0.78 | PKM (0.40) | POLBLMNA | |
| SCHEMBL14196007 | 0.78 | IRAK4 (0.35) | IRAK4FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008055959-A1 | NOVEL COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE & INFLAMMATORY DISEASES | GALAPAGOS N.V. (BE) | 2008-05-15 | — | — | WO | disclosed |