Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2759573 | 0.81 | NPC1 (0.50) | ALDH1A1MEN1KMT2AGAAMAPK8 | |
| SCHEMBL4888849 | 0.81 | HDAC1 (0.51) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL27787857 | 0.77 | NPC1 (0.50) | KDM4EALDH1A1KMT2AGAAHTT | |
| SCHEMBL15531453 | 0.76 | MAPT (0.52) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL27995877 | 0.75 | P4HTM (0.44) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5177261 | 0.74 | HDAC4 (0.49) | KDM4EMEN1KMT2AGAAALOX12 | |
| SCHEMBL27995879 | 0.74 | SCD (0.53) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL13451590 | 0.74 | MEN1 (0.54) | ALDH1A1MEN1KMT2AHSD17B10KCNH3 | |
| SCHEMBL25934308 | 0.73 | VNN1 (0.52) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL16020927 | 0.71 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064255-A2 | COMPOUNDS MODULATING C-FMS AND/OR C-KIT ACTIVITY AND USES THEREFOR | PLEXXIKON, INC. (US) | 2008-05-29 | — | — | WO | disclosed |