Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
| ▸ | VNN1 | O95497 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15531453 | 0.78 | MAPT (0.52) | P4HTMVNN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL14197864 | 0.75 | KDM4E (0.48) | P4HTMSMN1; SMN2LMNAGAAALDH1A1 | |
| SCHEMBL27995879 | 0.74 | SCD (0.53) | P4HTMVNN1SMN1; SMN2LMNAATG4B | |
| SCHEMBL4888849 | 0.72 | HDAC1 (0.51) | P4HTMVNN1SMN1; SMN2LMNAGAA | |
| SCHEMBL11394043 | 0.67 | P4HTM (0.67) | P4HTMVNN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL11387130 | 0.67 | P4HTM (0.56) | P4HTMVNN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL15010419 | 0.66 | FYN (0.49) | VNN1MAPTGAAATG4BNPC1 | |
| SCHEMBL7828381 | 0.66 | CCNE1 (0.67) | VNN1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL29071442 | 0.66 | RAB9A (0.74) | MAPTSMN1; SMN2LMNAGAAALDH1A1 | |
| SCHEMBL27518079 | 0.66 | VNN1 (0.40) | VNN1MAPTSMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104271572-A | Thiazolecarboxamide derivatives for use as nampt inhibitors | ABBVIE INC | 2015-01-07 | — | — | CN | disclosed |