Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | UBE2N | P61088 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14198065 | 0.94 | HPGD (0.61) | ALDH1A1HPGDAPPKMT2AKDM4E | |
| SCHEMBL14198022 | 0.87 | SMN1; SMN2 (0.59) | ALDH1A1HPGDL3MBTL1LMNAKMT2A | |
| SCHEMBL5350800 | 0.87 | ALDH1A1 (0.58) | AMY1AALDH1A1HPGDL3MBTL1APP | |
| SCHEMBL5362058 | 0.87 | ALDH1A1 (0.58) | AMY1AALDH1A1HPGDL3MBTL1APP | |
| SCHEMBL7354893 | 0.87 | ALDH1A1 (0.58) | AMY1AALDH1A1HPGDL3MBTL1APP | |
| SCHEMBL4960972 | 0.87 | APP (0.56) | AMY1AALDH1A1HPGDL3MBTL1APP | |
| SCHEMBL4960977 | 0.87 | APP (0.56) | AMY1AALDH1A1HPGDL3MBTL1APP | |
| SCHEMBL5362060 | 0.87 | ALDH1A1 (0.58) | AMY1AALDH1A1HPGDL3MBTL1APP | |
| SCHEMBL5350808 | 0.87 | ALDH1A1 (0.58) | AMY1AALDH1A1HPGDL3MBTL1APP | |
| SCHEMBL7356814 | 0.87 | ALDH1A1 (0.58) | AMY1AALDH1A1HPGDL3MBTL1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096894-A1 | Anti-Bacterial Compounds | ASTON UNIVERSITY (GB) | 2008-04-24 | — | — | US | disclosed |
| US-20080096894-A1 | Anti-Bacterial Compounds | ASTON UNIVERSITY (GB) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096894-A1 | Anti-Bacterial Compounds | MRPL21, PGLS, FOSB | AMY1A 927/4885ALDH1A1 3322/4885HPGD 1861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.