Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
| ▸ | GABRE | P78334 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16818091 | 0.77 | TYMP (0.39) | CDK5CDK5R1ADORA3MEN1KMT2A | |
| SCHEMBL4172313 | 0.73 | CDK5 (0.50) | CDK5CDK5R1AURKALMNAMAPT | |
| SCHEMBL699273 | 0.73 | LMNA (0.65) | AURKALMNAMAPTDAOHSP90AA1 | |
| SCHEMBL29367625 | 0.73 | LMNA (0.65) | AURKALMNAMAPTDAOHSP90AA1 | |
| SCHEMBL23119573 | 0.72 | CDK5 (0.59) | CDK5CDK5R1AURKALMNAMAPT | |
| SCHEMBL31151770 | 0.72 | KDM4E (0.46) | LMNAMAPTKDM4EPOLBMEN1 | |
| SCHEMBL7139964 | 0.72 | KDM4E (0.46) | LMNAMAPTKDM4EPOLBMEN1 | |
| SCHEMBL7949067 | 0.72 | POLB (0.33) | CDK5CDK5R1LMNAMAPTKDM4E | |
| SCHEMBL30583952 | 0.69 | GABRP (0.56) | CDK5CDK5R1AURKALMNAMAPT | |
| SCHEMBL23119726 | 0.69 | HSP90AA1 (0.56) | AURKALMNAMAPTDAOHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105829430-A | Sulfenamides as flame retardants | 松原国际股份有限公司 | 2016-08-03 | — | — | CN | claimed |
| CN-105829430-A | Sulfenamides as flame retardants | 松原国际股份有限公司 | 2016-08-03 | — | — | CN | disclosed |
| EP-1608627-B1 | BICYCLIC ANILIDE SPIROHYDANTOIN CGRP RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2008-05-07 | — | — | EP | disclosed |
| US-7202251-B2 | Bicyclic anilide spirohydantoin CGRP receptor antagonists | MERCK & CO., INC. (US) | 2007-04-10 | — | — | US | disclosed |
| US-7202251-B2 | Bicyclic anilide spirohydantoin CGRP receptor antagonists | MERCK & CO., INC. (US) | 2007-04-10 | — | — | US | disclosed |