Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | AURKA | O14965 | 2/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TNKS | O95271 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.50 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.50 |
| ▸ | GABRD | O14764 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29367625 | 1.00 | LMNA (0.65) | LMNAMEN1KMT2AL3MBTL1AURKA | |
| SCHEMBL23119573 | 0.87 | CDK5 (0.59) | LMNAMEN1KMT2AL3MBTL1AURKA | |
| SCHEMBL8156714 | 0.85 | GABRP (0.52) | LMNAMEN1KMT2AL3MBTL1AURKA | |
| SCHEMBL4098385 | 0.85 | AURKA (0.56) | LMNAMEN1KMT2AL3MBTL1AURKA | |
| SCHEMBL23119669 | 0.85 | LMNA (0.67) | LMNAMEN1KMT2AL3MBTL1AURKA | |
| SCHEMBL9994946 | 0.85 | HTT (0.56) | LMNAMEN1KMT2AL3MBTL1AURKA | |
| SCHEMBL16634744 | 0.85 | L3MBTL1 (0.55) | LMNAMEN1KMT2AL3MBTL1AURKA | |
| SCHEMBL18919887 | 0.84 | L3MBTL1 (0.57) | LMNAMEN1KMT2AL3MBTL1AURKA | |
| SCHEMBL21463671 | 0.83 | DAO (0.50) | LMNAMEN1KMT2AL3MBTL1AURKA | |
| SCHEMBL10743256 | 0.83 | KDM4E (0.73) | LMNAMEN1KMT2AL3MBTL1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039409-A2 | COMPOSITION COMPRISING ACTIVATORS OF IK POTASSIUM CHANNELS AND CALCINEURIN ANTAGONISTS AND USE THEREOF | SWITCH BIOTECH AG (DE) | 2004-05-13 | — | — | WO | claimed |
| US-11802120-B2 | Fused cyclic urea derivatives as CRHR2 antagonist | RAQUALIA PHARMA INC. (JP) | 2023-10-31 | — | — | US | disclosed |
| US-11802120-B2 | Fused cyclic urea derivatives as CRHR2 antagonist | RAQUALIA PHARMA INC. (JP) | 2023-10-31 | — | — | US | disclosed |
| EP-3774739-B1 | FUSED CYCLIC UREA DERIVATIVES AS CRHR2 ANTAGONIST | RAQUALIA PHARMA INC (JP) | 2022-05-11 | — | — | EP | disclosed |
| US-11174258-B2 | Benzimidazolo[1,2-a]benzimidazole derivatives for organic light emitting diodes | IDEMITSU KOSAN CO., LTD. (JP) | 2021-11-16 | — | — | US | disclosed |
| US-11174258-B2 | Benzimidazolo[1,2-a]benzimidazole derivatives for organic light emitting diodes | IDEMITSU KOSAN CO., LTD. (JP) | 2021-11-16 | — | — | US | disclosed |
| EP-3356368-B1 | BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLYL GROUPS, CARBAZOLYL GROUPS, BENZOFURANE GROUPS OR BENZOTHIOPHENE GROUPS FOR ORGANIC LIGHT EMITTING DIODES | IDEMITSU KOSAN CO (JP) | 2021-07-21 | — | — | EP | disclosed |
| EP-3356368-B1 | BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLYL GROUPS, CARBAZOLYL GROUPS, BENZOFURANE GROUPS OR BENZOTHIOPHENE GROUPS FOR ORGANIC LIGHT EMITTING DIODES | IDEMITSU KOSAN CO (JP) | 2021-07-21 | — | — | EP | disclosed |
| US-20210078975-A1 | FUSED CYCLIC UREA DERIVATIVES AS CRHR2 ANTAGONIST | RAQUALIA PHARMA INC. (JP) | 2021-03-18 | — | — | US | disclosed |
| US-20190002469-A1 | BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES | IDEMITSU KOSAN CO., LTD. (JP) | 2019-01-03 | — | — | US | disclosed |
| EP-0320992-B1 | Triazolodiazepine derivatives | HOFFMANN LA ROCHE (CH) | 1994-07-27 | — | — | EP | disclosed |
| US-5280030-A | Containing 1-benz(oxazole, thiazole or imidazole)-4-imidazole piperidine compound | SYNTHELABO (FR) | 1994-01-18 | — | — | US | disclosed |
| CN-1065459-A | Piperidine derivative and preparation method thereof is used with treatment | SYNTHELABO (FR) | 1992-10-21 | — | — | CN | disclosed |
| EP-0507650-A1 | Piperidine derivatives, their preparation and their therapeutic application | SYNTHELABO (FR) | 1992-10-07 | — | — | EP | disclosed |
| EP-0320992-A2 | Triazolodiazepine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-06-21 | — | — | EP | disclosed |
| US-4377695-A | ANTIINFLAMMATORY, ANALGESIC, ANTICOAGULANT AGENTS | A. NATTERMANN & CIE GMBH (DE) | 1983-03-22 | — | — | US | disclosed |
| EP-0051827-A1 | Omega-(2-oxo-benzimidazolinyl)-alkanoic acid derivatives, process for producing the same and pharmaceutical compounds containing the same | A. Nattermann & Cie. GmbH (DE) | 1982-05-19 | — | — | EP | disclosed |
| US-4275215-A | QUATERNARY AMMONIUM OR PHOSPHONIUM SALTS CATALYZE REACTION OF HYPOHALITE AND A DIPHENYL UREA | DOW CHEMICAL COMPANY LIMITED (GB) | 1981-06-23 | — | — | US | disclosed |
| US-4152434-A | ANTIDEPRESSANTS | HEXACHIMIE (FR) | 1979-05-01 | — | — | US | disclosed |
| US-4122175-A | ANTIDEPRESSANTS | HEXACHIMIE (FR) | 1978-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11174258-B2 | Benzimidazolo[1,2-a]benzimidazole derivatives for organic light emitting diodes | KCNH2, KCNH3, KCNJ2 | LMNA 979/4885MEN1 3653/4885KMT2A 1719/4885 |
| US-20190002469-A1 | BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES | KCNH2, KCNH3, KCNJ2 | LMNA 979/4885MEN1 3653/4885KMT2A 1719/4885 |
| US-20210078975-A1 | FUSED CYCLIC UREA DERIVATIVES AS CRHR2 ANTAGONIST | CRHR2, CRHR1, CRH | LMNA 3635/4885MEN1 2330/4885KMT2A 4119/4885 |
| US-11802120-B2 | Fused cyclic urea derivatives as CRHR2 antagonist | CRHR2, CRHR1, CRH | LMNA 3635/4885MEN1 2330/4885KMT2A 4119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.