Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.80 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4315481 | 0.89 | LMNA (1.00) | LMNAKMT2AGAAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28857355 | 0.88 | LMNA (0.97) | LMNAKMT2AGAAHTTSMN1; SMN2 | |
| Iodide SCHEMBL30758614 | 0.88 | LMNA (0.97) | LMNAKMT2AGAAHTTSMN1; SMN2 | |
| SCHEMBL24574897 | 0.82 | LMNA (0.85) | LMNAKMT2AGAAHTTSMN1; SMN2 | |
| SCHEMBL8460947 | 0.80 | LMNA (0.81) | LMNAKMT2AGAAHTTSMN1; SMN2 | |
| SCHEMBL16203606 | 0.79 | KMT2A (0.79) | LMNAKMT2AGAAHTTSMN1; SMN2 | |
| SCHEMBL10210763 | 0.79 | POLB (0.53) | LMNAKMT2A | |
| SCHEMBL16203451 | 0.78 | LMNA (0.77) | LMNAKMT2AGAAHTTSMN1; SMN2 | |
| SCHEMBL13129151 | 0.77 | LMNA (0.69) | LMNAKMT2AGAAHTTSMN1; SMN2 | |
| SCHEMBL16591365 | 0.77 | LMNA (0.74) | LMNAKMT2AGAAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664132-B1 | POLYMERIZATION CATALYSTS, PREPARATION OF POLYOLEFINS, ORGANOTRANSITION METAL COMPOUNDS AND LIGANDS | BASELL POLYOLEFINE GMBH (DE) | 2008-05-07 | — | — | EP | disclosed |