SCHEMBL4315481

SCHEMBL4315481

CC(C)c1cccc(C(C)C)c1NC(=O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 1.00
KMT2A Q03164 1/20 1.00
GAA P10253 1/20 0.59
HTT P42858 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.56
SOAT2 O75908 1/20 0.52
SOAT1 P35610 1/20 0.52
KCNK3 O14649 2/20 0.51
KCNK9 Q9NPC2 2/20 0.51
LPAR1 Q92633 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL30758614 0.98 LMNA (0.97) LMNAKMT2AGAAHTTSMN1; SMN2
Hydrochloric Acid SCHEMBL28857355 0.98 LMNA (0.97) LMNAKMT2AGAAHTTSMN1; SMN2
SCHEMBL24574897 0.92 LMNA (0.85) LMNAKMT2AGAAHTTSMN1; SMN2
SCHEMBL8460947 0.90 LMNA (0.81) LMNAKMT2AGAAHTTSMN1; SMN2
SCHEMBL14199811 0.89 LMNA (0.80) LMNAKMT2AGAAHTTSMN1; SMN2
SCHEMBL16203606 0.89 KMT2A (0.79) LMNAKMT2AGAAHTTSMN1; SMN2
SCHEMBL16203451 0.88 LMNA (0.77) LMNAKMT2AGAAHTTSMN1; SMN2
SCHEMBL16591365 0.85 LMNA (0.74) LMNAKMT2AGAAHTTSMN1; SMN2
SCHEMBL19138403 0.85 KMT2A (0.73) LMNAKMT2ASMN1; SMN2LPAR1
SCHEMBL16203502 0.84 LMNA (0.71) LMNAKMT2AGAAHTTKCNK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240317917-A1 METHODS FOR HYDROAMINOALKYLATION OF OLEFINS AND GROUP 4 METAL COMPLEXES USEFUL IN SUCH METHODS UNIV BRITISH COLUMBIA (CA) 2024-09-26 US disclosed
WO-2022133594-A1 METHODS FOR HYDROAMINOALKYLATION OF OLEFINS AND GROUP 4 METAL COMPLEXES USEFUL IN SUCH METHODS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2022-06-30 WO disclosed
WO-2022133594-A1 METHODS FOR HYDROAMINOALKYLATION OF OLEFINS AND GROUP 4 METAL COMPLEXES USEFUL IN SUCH METHODS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2022-06-30 WO disclosed
EP-3436488-B1 AN OLEFIN POLYMERIZATION CATALYST DOW GLOBAL TECHNOLOGIES LLC (US) 2022-05-18 EP disclosed
CN-108779205-B Olefin polymerization catalyst 陶氏环球技术有限责任公司 2022-01-07 CN disclosed
US-10975172-B2 Olefin polymerization catalyst DOW GLOBAL TECHNOLOGIES LLC (US) 2021-04-13 US disclosed
US-20200299420-A1 OLEFIN POLYMERIZATION CATALYST DOW GLOBAL TECHNOLOGIES LLC (US) 2020-09-24 US disclosed
WO-2019199519-A1 MIXED CATALYST SYSTEMS CONTAINING IRON TRIDENTATE CARBENES AND METHODS FOR MAKING POLYMER PRODUCTS USING SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-10-17 WO disclosed
US-20190308181-A1 Mixed Catalyst Systems Containing Iron Tridentate Carbenes and Methods for Making Polymer Products Using Same EXXONMOBIL CHEMICAL PATENTS INC. 2019-10-10 US disclosed
EP-3436488-A1 AN OLEFIN POLYMERIZATION CATALYST Dow Global Technologies, LLC (US) 2019-02-06 EP disclosed
EP-1664132-A1 POLYMERIZATION CATALYSTS, PREPARATION OF POLYOLEFINS, ORGANOTRANSITION METAL COMPOUNDS AND LIGANDS Basell Polyolefine GmbH (DE) 2006-06-07 EP disclosed
US-6969748-B2 Metal complexes of iminohydroxamic acids BASF AKTIENGESELLSCHAFT (DE) 2005-11-29 US disclosed
US-20050085603-A1 Metal complexes of iminohydroxamic acids BASF AKIENGESELLSCHAFT (DE) 2005-04-21 US disclosed
WO-2005030813-A1 POLYMERIZATION CATALYSTS, PREPARATION OF POLYOLEFINS, ORGANOTRANSITION METAL COMPOUNDS AND LIGANDS BASELL POLYOLEFINE GMBH (DE) 2005-04-07 WO disclosed
US-6846771-B2 Metal complexes of iminohydroxamic acids BASF AKTIENGESELLSCHAFT (DE) 2005-01-25 US disclosed
US-6828454-B2 Refluxing N-(2,6-diisopropylphenyl)benzamide and dimethyl hydrazine or methylhydroxylamine, to form ligand, then complexing metal halides, to form polymerization catalysts BASF AKTIENGESELLSCHAFT (DE) 2004-12-07 US disclosed
US-20030195111-A1 Metal complexes of iminohydroxamic acids BASF AKTIENGESELLSCHAFT (DE) 2003-10-16 US disclosed
US-20030191255-A1 Metal complexes of iminohydroxamic acids BASF AKTIENGESELLSCHAFT (DE) 2003-10-09 US disclosed
EP-1336613-A2 Metal complexes with iminohydroxamic acid as a ligand BASF AKTIENGESELLSCHAFT (DE) 2003-08-20 EP disclosed
EP-1336615-A2 Metal complexes with iminohyrdoxamic acid as a ligand BASF AKTIENGESELLSCHAFT (DE) 2003-08-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030191255-A1 Metal complexes of iminohydroxamic acids ACOX1, ACAD9, NDUFAB1 LMNA 1466/4885KMT2A 3063/4885GAA 2387/4885
US-20050085603-A1 Metal complexes of iminohydroxamic acids ACAD9, INTS9, ETFA LMNA 533/4885KMT2A 2704/4885GAA 2881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.