SCHEMBL13129151

SCHEMBL13129151

CC(C)c1cc(Cc2cc(C(C)C)c(NC(=O)c3ccccc3)c(C(C)C)c2)cc(C(C)C)c1NC(=O)c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.69
KMT2A Q03164 1/20 0.69
HTT P42858 3/20 0.56
GAA P10253 1/20 0.56
LTC4S Q16873 1/20 0.48
SOAT2 O75908 1/20 0.44
SOAT1 P35610 1/20 0.44
KCNK3 O14649 1/20 0.44
KCNK9 Q9NPC2 1/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
MAPT P10636 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
BCL2 P10415 1/20 0.43
MCL1 Q07820 1/20 0.43
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4315481 0.82 LMNA (1.00) LMNAKMT2AHTTGAASOAT2
Hydrochloric Acid SCHEMBL28857355 0.81 LMNA (0.97) LMNAKMT2AHTTGAASOAT2
Iodide SCHEMBL30758614 0.81 LMNA (0.97) LMNAKMT2AHTTGAASOAT2
SCHEMBL12284720 0.81 HTT (0.55) LMNAKMT2AHTTGAALTC4S
SCHEMBL12285477 0.78 KDM4E (0.54) LMNAKMT2AHTTLTC4SKCNK3
SCHEMBL14199811 0.77 LMNA (0.80) LMNAKMT2AHTTGAASOAT2
SCHEMBL24574897 0.76 LMNA (0.85) LMNAKMT2AHTTGAASOAT2
SCHEMBL16203408 0.75 LMNA (0.60) LMNAKMT2AHTTGAANPC1
SCHEMBL13129140 0.75 KDM4E (0.50) LMNAKMT2AHTTGAALTC4S
SCHEMBL16566894 0.74 KMT2A (0.58) LMNAKMT2AHTTGAANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8420721-B2 Polyolefin resin composition ADEKA CORPORATION (JP) 2013-04-16 US disclosed
US-20100240815-A1 POLYOLEFIN RESIN COMPOSITION ADEKA CORPORATION (JP) 2010-09-23 US disclosed