Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3535955 | 0.90 | HPGD (0.46) | HPGDTSHRAPEX1MAPTALDH1A1 | |
| SCHEMBL3538298 | 0.82 | HPGD (0.41) | HPGDTSHRAPEX1MAPTALDH1A1 | |
| SCHEMBL3540319 | 0.81 | PTGER4 (0.56) | HPGDTSHRMAPTALDH1A1KDM4E | |
| SCHEMBL14199639 | 0.77 | MAPT (0.67) | HPGDTSHRMAPTALDH1A1KDM4E | |
| SCHEMBL3534389 | 0.75 | TSHR (0.56) | HPGDTSHRAPEX1MAPTALDH1A1 | |
| SCHEMBL3534546 | 0.73 | TSHR (0.55) | HPGDTSHRAPEX1MAPTALDH1A1 | |
| SCHEMBL28606522 | 0.70 | HPGD (0.52) | HPGDMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL6825954 | 0.69 | L3MBTL1 (0.51) | HPGDTSHRMAPTALDH1A1KDM4E | |
| SCHEMBL3531970 | 0.69 | PTGER4 (0.71) | APEX1POLB | |
| SCHEMBL12554580 | 0.69 | L3MBTL1 (0.52) | HPGDMAPTALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603893-B1 | EP4 RECEPTOR ANTAGONISTS | ASTERAND UK LTD (GB) | 2008-05-21 | — | — | EP | disclosed |