Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10128665 | 1.00 | HSD17B1 (0.35) | HSD17B1HSD17B2SIGMAR1ALDH1A1MAPT | |
| SCHEMBL13089941 | 0.96 | ALDH1A1 (0.33) | HSD17B1HSD17B2SIGMAR1ALDH1A1MAPT | |
| SCHEMBL25786556 | 0.93 | HSD17B1 (0.35) | HSD17B1HSD17B2SIGMAR1ALDH1A1MAPT | |
| SCHEMBL25786577 | 0.93 | HSD17B1 (0.37) | HSD17B1HSD17B2SIGMAR1ALDH1A1MAPT | |
| SCHEMBL25786514 | 0.89 | CYP1A2 (0.40) | HSD17B1HSD17B2SIGMAR1ALDH1A1MAPT | |
| SCHEMBL4545233 | 0.89 | GPR84 (0.38) | ALDH1A1MAPTKDM4ETDP1L3MBTL1 | |
| SCHEMBL18433942 | 0.88 | HSD17B1 (0.41) | HSD17B1HSD17B2SIGMAR1ALDH1A1MAPT | |
| SCHEMBL22151752 | 0.87 | CYP11B1 (0.39) | HSD17B1HSD17B2SIGMAR1ALDH1A1MAPT | |
| SCHEMBL1753730 | 0.87 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4ETDP1L3MBTL1 | |
| SCHEMBL9971761 | 0.87 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4ETDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926159-A1 | ASYMMETRIC FLUORENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THE SAME | IDEMITSU KOSAN COMPANY LIMITED (JP) | 2008-05-28 | — | — | EP | disclosed |