Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14200214 | 0.90 | CA1 (0.36) | — | |
| SCHEMBL14228926 | 0.90 | CES1 (0.40) | CES1 | |
| SCHEMBL14200221 | 0.87 | CES1 (0.33) | CES1 | |
| SCHEMBL14200209 | 0.87 | CES1 (0.33) | CES1 | |
| SCHEMBL14228929 | 0.87 | CA1 (0.39) | CES1 | |
| SCHEMBL14200186 | 0.83 | CA1 (0.34) | — | |
| SCHEMBL14200211 | 0.82 | — | — | |
| SCHEMBL14200414 | 0.80 | CNR1 (0.32) | — | |
| SCHEMBL14229202 | 0.80 | RORC (0.34) | CES1 | |
| SCHEMBL14229197 | 0.79 | CES1 (0.35) | CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |