Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14200214 | 0.83 | CA1 (0.36) | — | |
| SCHEMBL14200422 | 0.82 | — | — | |
| SCHEMBL14229202 | 0.82 | RORC (0.34) | RORC | |
| SCHEMBL14200216 | 0.80 | CES1 (0.34) | — | |
| SCHEMBL14200420 | 0.80 | CNR1 (0.32) | CNR1CNR2 | |
| SCHEMBL19767020 | 0.78 | PIK3CD (0.33) | CNR1CNR2 | |
| SCHEMBL14200426 | 0.78 | — | — | |
| SCHEMBL14200421 | 0.78 | PIK3CD (0.34) | — | |
| SCHEMBL14200413 | 0.76 | PIK3CD (0.36) | — | |
| SCHEMBL14200429 | 0.75 | CNR1 (0.32) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |