Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14200417 | 0.95 | BMP1 (0.32) | BMP1CNR2 | |
| SCHEMBL14200416 | 0.94 | CNR2 (0.34) | BMP1CNR2 | |
| SCHEMBL14200201 | 0.88 | BMP1 (0.35) | BMP1CNR2 | |
| SCHEMBL14200411 | 0.86 | — | — | |
| SCHEMBL14201305 | 0.85 | CA1 (0.40) | BMP1CNR2 | |
| SCHEMBL14200218 | 0.85 | CNR2 (0.39) | BMP1CNR2 | |
| SCHEMBL14229149 | 0.85 | BMP1 (0.41) | BMP1CNR2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14201302 | 0.84 | CA1 (0.36) | — | |
| SCHEMBL14200349 | 0.82 | CNR2 (0.39) | BMP1CNR2 | |
| SCHEMBL14200420 | 0.81 | CNR1 (0.32) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |