SCHEMBL142005

SCHEMBL142005

COC(=O)c1ccc(C(=O)Oc2cc(C)c(C(C)(C)c3c(C)cc(OC)cc3C)c(C)c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 2/20 0.51
▸ CA2 P00918 2/20 0.51
▸ KMT2A Q03164 5/20 0.49
▸ TDP1 Q9NUW8 1/20 0.45
▸ HPGD P15428 2/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ POLB P06746 2/20 0.44
▸ MAPT P10636 3/20 0.43
▸ MEN1 O00255 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ ACR P10323 2/20 0.43
▸ HGFAC Q04756 1/20 0.43
▸ PRSS1 P07477 1/20 0.42
▸ CA12 O43570 1/20 0.41
▸ CA7 P43166 1/20 0.41
▸ CA9 Q16790 1/20 0.41
▸ CA14 Q9ULX7 1/20 0.41
▸ LMNA P02545 2/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14007583 0.84 ESR1 (0.47) KMT2ATDP1CYP3A4POLBMAPT
SCHEMBL141562 0.81 ESR1 (0.49) KMT2ACYP3A4POLBMAPTMEN1
SCHEMBL14701064 0.79 KMT2A (0.42) KMT2AHPGDCYP3A4POLBMAPT
SCHEMBL141627 0.75 CA1 (0.66) CA1CA2KMT2ATDP1MAPT
SCHEMBL13038154 0.74 CA1 (0.84) CA1CA2KMT2APOLBMAPT
SCHEMBL14579686 0.74 KMT2A (0.50) CA1CA2KMT2APOLBMAPT
SCHEMBL13913170 0.72 KMT2A (0.61) CA1CA2KMT2AHPGDCYP3A4
SCHEMBL16357038 0.72 ACR (0.56) CA1CA2KMT2ATDP1POLB
SCHEMBL7518320 0.72 CA1 (0.72) CA1CA2KMT2ATDP1POLB
SCHEMBL11031812 0.72 CA1 (0.57) CA1CA2KMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9442400-B2 Electrophotographic photoreceptor including a copolymer polyarylate resin, production method therefor, electrophotographic device including the photoreceptor, and production method for the copolymer polyarylate resin FUJI ELECTRIC CO., LTD. (JP) 2016-09-13 — — US disclosed
US-20150079510-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PRODUCTION METHOD THEREFOR, ELECTROPHOTOGRAPHIC DEVICE, AND PRODUCTION METHOD FOR COPOLYMER POLYARYLATE RESIN FUJI ELECTRIC CO., LTD. (JP) 2015-03-19 — — US disclosed
US-8404414-B2 Electrophotographic photoconductor and manufacturing method thereof FUJI ELECTRIC CO., LTD. (JP) 2013-03-26 — — US disclosed
US-20120058422-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, PROCESS FOR PRODUCING THE SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD (JP) 2012-03-08 — — US disclosed
US-20110189603-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND MANUFACTURING METHOD THEREOF FUJI ELECTRIC SYSTEMS CO., LTD. (JP) 2011-08-04 — — US disclosed
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