Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | ACR | P10323 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14579687 | 0.81 | KMT2A (0.47) | KMT2AMAPTGAATP53POLB | |
| SCHEMBL14579685 | 0.79 | BACE1 (0.50) | KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL14007583 | 0.79 | ESR1 (0.47) | KMT2AMAPTPOLBMEN1CYP1A2 | |
| SCHEMBL11911278 | 0.79 | LMNA (0.66) | KMT2AMAPTLMNACYP1A2CYP2C9 | |
| SCHEMBL14579689 | 0.78 | KMT2A (0.49) | KMT2AMAPTLMNACYP1A2CYP2C9 | |
| SCHEMBL14579669 | 0.76 | PRSS1 (0.65) | KMT2AMAPTTP53MEN1LMNA | |
| SCHEMBL14579671 | 0.76 | KMT2A (0.61) | KMT2AMAPTPOLBMEN1LMNA | |
| SCHEMBL13258485 | 0.75 | ESR1 (0.52) | KMT2AMAPTTP53MEN1CYP1A2 | |
| SCHEMBL12895853 | 0.75 | KMT2A (0.64) | KMT2AMAPTPOLBMEN1LMNA | |
| SCHEMBL2742858 | 0.74 | LMNA (0.60) | KMT2AMAPTLMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7175955-B2 | Electrophotographic photoreceptor, electrophotographic process cartridge and image forming apparatus | FUJI XEROX CO., LTD. (JP) | 2007-02-13 | — | — | US | disclosed |