Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14201092 | 0.93 | HDAC7 (0.31) | — | |
| SCHEMBL14201428 | 0.90 | CA2 (0.35) | CA1CA2 | |
| SCHEMBL14201072 | 0.89 | CA2 (0.34) | CA1CA2 | |
| SCHEMBL14201099 | 0.87 | CA2 (0.35) | CA1CA2 | |
| SCHEMBL14201044 | 0.83 | CA1 (0.33) | CA1CA2 | |
| SCHEMBL14201043 | 0.81 | CA1 (0.37) | CA1CA2 | |
| SCHEMBL14229276 | 0.80 | ALDH1A1 (0.33) | — | |
| SCHEMBL14200905 | 0.80 | GPR84 (0.37) | CA2 | |
| SCHEMBL14201134 | 0.80 | CA2 (0.35) | CA1CA2 | |
| SCHEMBL14201070 | 0.79 | CA2 (0.32) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |