Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.81 |
| ▸ | LMNA | P02545 | 3/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.81 |
| ▸ | HPGD | P15428 | 2/20 | 0.81 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.81 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.81 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.81 |
| ▸ | GAA | P10253 | 1/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.81 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.81 |
| ▸ | CBR1 | P16152 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | STAT3 | P40763 | 1/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.61 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21662430 | 1.00 | ALDH1A1 (0.81) | ALDH1A1LMNASMN1; SMN2CYP3A4HPGD | |
| Zearalenone SCHEMBL33754 | 0.90 | ALDH1A1 (1.00) | ALDH1A1LMNASMN1; SMN2CYP3A4HPGD | |
| Zearalenone SCHEMBL29354213 | 0.90 | ALDH1A1 (1.00) | ALDH1A1LMNASMN1; SMN2CYP3A4HPGD | |
| Zearalenone SCHEMBL33755 | 0.90 | ALDH1A1 (1.00) | ALDH1A1LMNASMN1; SMN2CYP3A4HPGD | |
| Zearalenone SCHEMBL588840 | 0.90 | ALDH1A1 (1.00) | ALDH1A1LMNASMN1; SMN2CYP3A4HPGD | |
| Zearalenone SCHEMBL588842 | 0.90 | ALDH1A1 (1.00) | ALDH1A1LMNASMN1; SMN2CYP3A4HPGD | |
| Zearalenone SCHEMBL588841 | 0.90 | ALDH1A1 (1.00) | ALDH1A1LMNASMN1; SMN2CYP3A4HPGD | |
| Zearalenone SCHEMBL28179514 | 0.89 | ALDH1A1 (0.98) | ALDH1A1LMNASMN1; SMN2CYP3A4HPGD | |
| Zearalenone SCHEMBL23827347 | 0.86 | ALDH1A1 (0.92) | ALDH1A1LMNASMN1; SMN2CYP3A4HPGD | |
| Zearalenone SCHEMBL28547269 | 0.86 | ALDH1A1 (0.92) | ALDH1A1LMNASMN1; SMN2CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008049994-A1 | NEW FLUORENE DERIVATIVES, COMPOSITIONS CONTAINING THE SAME AND USE THEREOF AS INHIBITORS OF THE PROTEIN CHAPERONE HSP 90 | SANOFI-AVENTIS (FR) | 2008-05-02 | — | — | WO | disclosed |