Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 4/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14201175 | 0.92 | RIPK1 (0.34) | MLYCDRIPK1HDAC8S1PR1 | |
| SCHEMBL14201121 | 0.89 | MLYCD (0.32) | MLYCDPOLBS1PR1 | |
| SCHEMBL14229322 | 0.86 | MLYCD (0.33) | MLYCDPOLB | |
| SCHEMBL14201177 | 0.86 | RIPK1 (0.34) | MLYCDRIPK1HDAC8S1PR1 | |
| SCHEMBL14200495 | 0.84 | RIPK1 (0.34) | MLYCDRIPK1POLBHDAC8 | |
| SCHEMBL14229295 | 0.84 | RIPK1 (0.44) | MLYCDRIPK1POLB | |
| SCHEMBL14201157 | 0.84 | RIPK1 (0.34) | MLYCDRIPK1POLBHDAC8 | |
| SCHEMBL14230197 | 0.82 | MEN1 (0.33) | MLYCDPOLB | |
| SCHEMBL14201172 | 0.81 | SCN5A (0.40) | S1PR1 | |
| SCHEMBL14201120 | 0.81 | MAPK1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |