Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14201160 | 0.92 | S1PR1 (0.33) | MLYCDS1PR1 | |
| SCHEMBL14230193 | 0.91 | MLYCD (0.31) | MLYCDS1PR1POLBPPARGPPARD | |
| SCHEMBL14201176 | 0.89 | MLYCD (0.34) | MLYCDS1PR1POLB | |
| SCHEMBL14201158 | 0.88 | MLYCD (0.33) | MLYCDS1PR1POLBPPARGPPARD | |
| SCHEMBL14201194 | 0.87 | S1PR1 (0.32) | S1PR1POLB | |
| SCHEMBL14229079 | 0.86 | POLB (0.33) | MLYCDS1PR1POLB | |
| SCHEMBL14201180 | 0.86 | S1PR1 (0.34) | MLYCDS1PR1 | |
| SCHEMBL14229081 | 0.84 | RIPK1 (0.39) | — | |
| SCHEMBL14201151 | 0.84 | POLB (0.32) | MLYCDPOLBPPARGPPARDPPARA | |
| SCHEMBL14200885 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |