Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | OSBP | P22059 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4977891 | 0.93 | OSBP (0.43) | MAOBMAOAOSBPMAPTKMT2A | |
| SCHEMBL4977898 | 0.93 | OSBP (0.43) | MAOBMAOAOSBPMAPTKMT2A | |
| SCHEMBL14518094 | 0.77 | MAOB (0.45) | MAOBMAOAMAPTRAB9AKMT2A | |
| SCHEMBL14523859 | 0.76 | PTPN1 (0.47) | MAOBMAOAMAPTKMT2AMAPK1 | |
| SCHEMBL4982221 | 0.70 | PTPN1 (0.51) | MAOBMAPTKMT2AMAPK1ALDH1A1 | |
| SCHEMBL5519370 | 0.70 | PTPN1 (0.51) | MAOBMAPTKMT2AMAPK1ALDH1A1 | |
| SCHEMBL15620334 | 0.69 | NFKB1 (0.48) | MAOBMAOAMAPTKMT2AMAPK1 | |
| SCHEMBL15620335 | 0.65 | NFKB1 (0.48) | MAOBMAOAMAPTKMT2AMAPK1 | |
| SCHEMBL5997891 | 0.65 | MAOB (0.52) | MAOBMAOAMAPTKMT2AMAPK1 | |
| SCHEMBL14523845 | 0.65 | MAOB (0.52) | MAOBMAOAMAPTKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361774-B2 | Chalcone compound | TAKARA BIO INC. (JP) | 2008-04-22 | — | — | US | disclosed |