SCHEMBL14518094

SCHEMBL14518094

CC(C)=CCCC1(C)Oc2c(C(=O)/C=C/c3ccc(C)cc3)ccc(O)c2CC1O

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 5/20 0.45
▸ PTPN1 P18031 4/20 0.43
▸ DHODH Q02127 1/20 0.43
▸ MAPT P10636 5/20 0.43
▸ KMT2A Q03164 5/20 0.43
▸ ALDH1A1 P00352 2/20 0.43
▸ GAA P10253 2/20 0.43
▸ MEN1 O00255 2/20 0.43
▸ LMNA P02545 2/20 0.43
▸ MAOA P21397 2/20 0.40
▸ RAB9A P51151 3/20 0.38
▸ MAPK1 P28482 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ NPC1 O15118 2/20 0.37
▸ ATM Q13315 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5519370 0.94 PTPN1 (0.51) MAOBPTPN1DHODHMAPTKMT2A
SCHEMBL4982221 0.94 PTPN1 (0.51) MAOBPTPN1DHODHMAPTKMT2A
SCHEMBL14523859 0.77 PTPN1 (0.47) MAOBPTPN1DHODHMAPTKMT2A
SCHEMBL14201287 0.77 MAOB (0.43) MAOBMAPTKMT2AALDH1A1GAA
SCHEMBL4977898 0.70 OSBP (0.43) MAOBPTPN1DHODHMAPTKMT2A
SCHEMBL4977891 0.70 OSBP (0.43) MAOBPTPN1DHODHMAPTKMT2A
SCHEMBL15620334 0.69 NFKB1 (0.48) MAOBPTPN1DHODHMAPTKMT2A
SCHEMBL14523845 0.66 MAOB (0.52) MAOBPTPN1MAPTKMT2AALDH1A1
SCHEMBL5997891 0.66 MAOB (0.52) MAOBPTPN1MAPTKMT2AALDH1A1
SCHEMBL16406485 0.66 APP (0.45) MAOBPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070092587-A1 Extract from plant of japanese parsley family and process for producing the same TAKARA BIO INC. (JP) 2007-04-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070092587-A1 Extract from plant of japanese parsley family and process for producing the same ALDOA, FABP4, UGDH MAOB 1273/4885PTPN1 3727/4885DHODH 1958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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