SCHEMBL14201531

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22511324	0.91	AURKA (0.53)	AURKAAURKBTTRSNCACYP1A2
	SCHEMBL15430100	0.80	MEN1 (0.40)	AURKAAURKBTTRSNCASUMO2
	SCHEMBL11147033	0.79	AURKB (0.53)	AURKAAURKBTTRSNCACYP1A2
	SCHEMBL2932464	0.79	AURKB (0.67)	AURKAAURKBTTRSNCACYP1A2
	SCHEMBL13515233	0.79	ALDH1A1 (0.51)	TTRSNCACHATCDK2ALDH1A1
	SCHEMBL7037649	0.79	AURKA (0.49)	AURKAAURKBTTRSNCACYP1A2
	SCHEMBL4510654	0.79	TTR (0.60)	AURKAAURKBTTRSNCACYP1A2
	SCHEMBL2662857	0.79	CYP1A2 (0.54)	AURKAAURKBTTRCYP1A2ATIC
	SCHEMBL30822934	0.78	AURKA (0.75)	AURKAAURKBTTRSNCACYP1A2
	SCHEMBL159398	0.78	AURKB (0.51)	AURKAAURKBTTRSNCACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.