Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | DUT | P33316 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14228844 | 0.85 | CA2 (0.42) | L3MBTL1TTRHTTALDH1A1HDAC6 | |
| SCHEMBL5024404 | 0.79 | TTR (0.47) | L3MBTL1TTRHTTHDAC6CYP1A2 | |
| SCHEMBL5016479 | 0.79 | TTR (0.47) | L3MBTL1TTRHTTHDAC6CYP1A2 | |
| SCHEMBL5016508 | 0.78 | TTR (0.46) | L3MBTL1TTRHTTHDAC6CYP1A2 | |
| SCHEMBL17381123 | 0.76 | TTR (0.50) | L3MBTL1TTRHTTHDAC6CYP1A2 | |
| SCHEMBL25255849 | 0.75 | TGM2 (0.42) | L3MBTL1TTRHTTALDH1A1HDAC6 | |
| SCHEMBL29892562 | 0.75 | TGM2 (0.42) | L3MBTL1TTRHTTALDH1A1HDAC6 | |
| SCHEMBL14201710 | 0.74 | NSD2 (0.43) | L3MBTL1TTRHTTALDH1A1CYP1A2 | |
| SCHEMBL8395506 | 0.71 | TTR (0.42) | L3MBTL1TTRHTTLMNAHDAC6 | |
| SCHEMBL8060497 | 0.71 | TTR (0.41) | L3MBTL1TTRHTTLMNAHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365223-B2 | Method for selective targeting of apoptotic cells and small molecule ligands used thereof | NST NEUROSURVIVAL TECHNOLOGIES LTD (IL) | 2008-04-29 | — | — | US | disclosed |