Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14228843 | 0.83 | TSHR (0.44) | L3MBTL1ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL14201709 | 0.78 | ALDH1A1 (0.56) | NSD2ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL5016478 | 0.77 | CNR1 (0.52) | L3MBTL1ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL5022978 | 0.77 | CNR1 (0.49) | L3MBTL1ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL14201706 | 0.74 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1TTRCYP1A2CYP2C19 | |
| SCHEMBL8395502 | 0.74 | NPC1 (0.56) | ALDH1A1HPGD | |
| SCHEMBL29892518 | 0.74 | NPC1 (0.56) | ALDH1A1HPGD | |
| SCHEMBL29892522 | 0.74 | NPC1 (0.56) | ALDH1A1HPGD | |
| SCHEMBL15282372 | 0.74 | TTR (0.47) | NSD2ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL29349851 | 0.74 | CA12 (0.54) | ALDH1A1KDM4EMAPTTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365223-B2 | Method for selective targeting of apoptotic cells and small molecule ligands used thereof | NST NEUROSURVIVAL TECHNOLOGIES LTD (IL) | 2008-04-29 | — | — | US | disclosed |