Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 8/20 | 1.00 |
| ▸ | PRKD3 | O94806 | 5/20 | 1.00 |
| ▸ | PRKCA | P17252 | 5/20 | 1.00 |
| ▸ | PRKCH | P24723 | 5/20 | 1.00 |
| ▸ | PRKCI | P41743 | 5/20 | 1.00 |
| ▸ | PRKCE | Q02156 | 5/20 | 1.00 |
| ▸ | PRKCD | Q05655 | 5/20 | 1.00 |
| ▸ | PRKD1 | Q15139 | 5/20 | 1.00 |
| ▸ | PRKCG | P05129 | 4/20 | 1.00 |
| ▸ | PRKCB | P05771 | 4/20 | 1.00 |
| ▸ | PRKCZ | Q05513 | 4/20 | 1.00 |
| ▸ | NTRK1 | P04629 | 7/20 | 0.90 |
| ▸ | KDR | P35968 | 7/20 | 0.90 |
| ▸ | FLT3 | P36888 | 5/20 | 0.84 |
| ▸ | MYLK | Q15746 | 4/20 | 0.84 |
| ▸ | CDK4 | P11802 | 3/20 | 0.84 |
| ▸ | CDK2 | P24941 | 3/20 | 0.84 |
| ▸ | MAP3K11 | Q16584 | 3/20 | 0.84 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.84 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14825402 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCAPRKCHPRKCI | |
| SCHEMBL13168059 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCAPRKCHPRKCI | |
| SCHEMBL29451226 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCAPRKCHPRKCI | |
| SCHEMBL16931994 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCAPRKCHPRKCI | |
| SCHEMBL3747539 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCAPRKCHPRKCI | |
| SCHEMBL29651606 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCAPRKCHPRKCI | |
| SCHEMBL13246716 | 0.94 | PRKCQ (0.89) | PRKCQPRKD3PRKCAPRKCHPRKCI | |
| K-252A SCHEMBL24112155 | 0.92 | NTRK1 (1.00) | PRKCQPRKD3PRKCAPRKCHPRKCI | |
| K-252A SCHEMBL968886 | 0.92 | NTRK1 (1.00) | PRKCQPRKD3PRKCAPRKCHPRKCI | |
| SCHEMBL21132411 | 0.92 | NTRK1 (0.85) | PRKCQPRKD3PRKCAPRKCHPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220249509-A1 | METHOD FOR PREVENTING HAIR LOSS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2022-08-11 | — | — | US | disclosed |
| US-20180179594-A1 | MULTIPLE SYSTEM ATROPHY AND THE TREATMENT THEREOF | PARKINSON'S INSTITUTE | 2018-06-28 | — | — | US | disclosed |
| US-20080081078-A1 | Prevention of Cell Proliferation by Inhibiting Myosin Light Chain Kinase | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-04-03 | — | — | US | disclosed |
| US-20080081078-A1 | Prevention of Cell Proliferation by Inhibiting Myosin Light Chain Kinase | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081078-A1 | Prevention of Cell Proliferation by Inhibiting Myosin Light Chain Kinase | MYLK3, MYLK, MYLK4 | PRKCQ 379/4885PRKD3 516/4885PRKCA 351/4885 |
| US-20220249509-A1 | METHOD FOR PREVENTING HAIR LOSS | MYLK3, MYLK4, MYLK | PRKCQ 716/4885PRKD3 1222/4885PRKCA 815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.