SCHEMBL29451226

SCHEMBL29451226

CC12OC(CC1(O)C(=O)O)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRKCQ Q04759 8/20 1.00
▸ PRKD3 O94806 5/20 1.00
▸ PRKCA P17252 5/20 1.00
▸ PRKCH P24723 5/20 1.00
▸ PRKCI P41743 5/20 1.00
▸ PRKCE Q02156 5/20 1.00
▸ PRKCD Q05655 5/20 1.00
▸ PRKD1 Q15139 5/20 1.00
▸ PRKCG P05129 4/20 1.00
▸ PRKCB P05771 4/20 1.00
▸ PRKCZ Q05513 4/20 1.00
▸ NTRK1 P04629 7/20 0.90
▸ KDR P35968 7/20 0.90
▸ FLT3 P36888 5/20 0.84
▸ MYLK Q15746 4/20 0.84
▸ CDK4 P11802 3/20 0.84
▸ CDK2 P24941 3/20 0.84
▸ MAP3K11 Q16584 3/20 0.84
▸ CAMKK2 Q96RR4 3/20 0.84
▸ DAPK3 O43293 2/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14825402 1.00 PRKCQ (1.00) PRKCQPRKD3PRKCAPRKCHPRKCI
SCHEMBL13168059 1.00 PRKCQ (1.00) PRKCQPRKD3PRKCAPRKCHPRKCI
SCHEMBL16931994 1.00 PRKCQ (1.00) PRKCQPRKD3PRKCAPRKCHPRKCI
SCHEMBL3747539 1.00 PRKCQ (1.00) PRKCQPRKD3PRKCAPRKCHPRKCI
SCHEMBL29651606 1.00 PRKCQ (1.00) PRKCQPRKD3PRKCAPRKCHPRKCI
SCHEMBL14207925 1.00 PRKCQ (1.00) PRKCQPRKD3PRKCAPRKCHPRKCI
SCHEMBL13246716 0.94 PRKCQ (0.89) PRKCQPRKD3PRKCAPRKCHPRKCI
K-252A SCHEMBL24112155 0.92 NTRK1 (1.00) PRKCQPRKD3PRKCAPRKCHPRKCI
K-252A SCHEMBL968886 0.92 NTRK1 (1.00) PRKCQPRKD3PRKCAPRKCHPRKCI
SCHEMBL21132411 0.92 NTRK1 (0.85) PRKCQPRKD3PRKCAPRKCHPRKCI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709377-A2 METHODS OF TREATMENT AND DIAGNOSIS OF PARKINSON'S DISEASE ASSOCIATED WITH WILD-TYPE LRRK2 Neuron23, Inc. (US) 2026-03-18 — — EP claimed
US-20260011407-A1 PREDICTIVE BIOMARKERS AND USE THEREOF TO TREAT PARKINSON'S DISEASE NEURON23 INC (US) 2026-01-08 — — US claimed
EP-4565328-A1 PREDICTIVE BIOMARKERS AND USE THEREOF TO TREAT PARKINSON'S DISEASE Neuron23, Inc. (US) 2025-06-11 — — EP claimed
CN-120051279-A Predictive biomarkers and their use for the treatment of parkinson's disease 神经元23公司 2025-05-27 — — CN claimed
WO-2024233854-A2 METHODS OF TREATMENT AND DIAGNOSIS OF PARKINSON'S DISEASE ASSOCIATED WITH WILD-TYPE LRRK2 NEURON23, INC. (US) 2024-11-14 — — WO claimed
WO-2024030504-A1 PREDICTIVE BIOMARKERS AND USE THEREOF TO TREAT PARKINSON'S DISEASE NEURON23, INC. (US) 2024-02-08 — — WO claimed
US-20230392206-A1 METHODS OF TREATMENT AND DIAGNOSIS OF PARKINSON'S DISEASE ASSOCIATED WITH WILD-TYPE LRRK2 NEURON23, INC. 2023-12-07 — — US claimed
CN-116940353-A Methods for the treatment and diagnosis of parkinson's disease associated with wild-type LRRK2 神经元23公司 2023-10-24 — — CN claimed
EP-4232024-A1 METHODS OF TREATMENT AND DIAGNOSIS OF PARKINSON'S DISEASE ASSOCIATED WITH WILD-TYPE LRRK2 Neuron23, Inc. (US) 2023-08-30 — — EP claimed
WO-2022093685-A1 METHODS OF TREATMENT AND DIAGNOSIS OF PARKINSON'S DISEASE ASSOCIATED WITH WILD-TYPE LRRK2 NEURON23, INC. (US) 2022-05-05 — — WO claimed
US-20260139289-A1 CONDITIONAL PRIMER EXTENSION FOR SINGLE-MOLECULE DETECTION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2026-05-21 — — US disclosed
EP-4709377-A2 METHODS OF TREATMENT AND DIAGNOSIS OF PARKINSON'S DISEASE ASSOCIATED WITH WILD-TYPE LRRK2 Neuron23, Inc. (US) 2026-03-18 — — EP disclosed
US-12533359-B2 Method for preventing hair loss ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2026-01-27 — — US disclosed
US-20260011407-A1 PREDICTIVE BIOMARKERS AND USE THEREOF TO TREAT PARKINSON'S DISEASE NEURON23 INC (US) 2026-01-08 — — US disclosed
EP-4665868-A2 METHODS FOR MULTIPLEXED IMAGING AND DETECTION OF TARGETS President and Fellows of Harvard College (US) 2025-12-24 — — EP disclosed
EP-3993764-A1 METHOD FOR PREVENTING HAIR LOSS Icahn School of Medicine at Mount Sinai (US) 2022-05-11 — — EP disclosed
WO-2022093685-A1 METHODS OF TREATMENT AND DIAGNOSIS OF PARKINSON'S DISEASE ASSOCIATED WITH WILD-TYPE LRRK2 NEURON23, INC. (US) 2022-05-05 — — WO disclosed
WO-2022076559-A1 METHODS, COMPOSITIONS, KITS AND SYSTEMS FOR SIGNAL-ON DETECTION OF NEUTRALIZATION TARGETS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-04-14 — — WO disclosed
EP-3974537-A1 MICROSCOPE-FREE IMAGING President and Fellows of Harvard College (US) 2022-03-30 — — EP disclosed
US-20220064699-A1 CONDITIONAL PRIMER EXTENSION FOR SINGLE-MOLECULE DETECTION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-03-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12533359-B2 Method for preventing hair loss MYLK, MYLK3, MYLK2 PRKCQ 133/4885PRKD3 202/4885PRKCA 76/4885
US-20260011407-A1 PREDICTIVE BIOMARKERS AND USE THEREOF TO TREAT PARKINSON'S DISEASE LRRK2, PARK7, BMP2K PRKCQ 831/4885PRKD3 938/4885PRKCA 1074/4885
US-20260139289-A1 CONDITIONAL PRIMER EXTENSION FOR SINGLE-MOLECULE DETECTION RNGTT, SSU72, CTDSP1 PRKCQ 1889/4885PRKD3 3706/4885PRKCA 2434/4885
US-20230392206-A1 METHODS OF TREATMENT AND DIAGNOSIS OF PARKINSON'S DISEASE ASSOCIATED WITH WILD-TYPE LRRK2 LRRK2, PARK7, PINK1 PRKCQ 125/4885PRKD3 323/4885PRKCA 109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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