Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 7/20 | 0.55 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30320686 | 0.89 | TOP2A (0.68) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL584841 | 0.89 | TOP2A (0.68) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL14208183 | 0.83 | KCNH2 (0.55) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL115991 | 0.82 | ADRB2 (0.62) | TOP2ATOP2BALDH1A1KMT2AKCNH2 | |
| SCHEMBL5777435 | 0.79 | MEN1 (0.55) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL10543241 | 0.79 | TOP2A (0.56) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL29463823 | 0.78 | TOP2A (0.71) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL500719 | 0.78 | TOP2A (0.71) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL10511115 | 0.77 | TOP2A (0.69) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL10510815 | 0.77 | TOP2A (0.69) | TOP2ATOP2BALDH1A1POLBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059521-A2 | NOVEL PROCESS FOR THE PREPARATION OF MOXIFLOXACIN HYDROCHLORIDE AND A NOVEL POLYMORPH OF MOXIFLOXACIN | MSN LABORATORIES LIMITED (IN) | 2008-05-22 | — | — | WO | disclosed |