Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS1 | P09382 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14213238 | 0.94 | LGALS1 (0.53) | LGALS1CYP1A2CYP2D6CYP2C19POLB | |
| SCHEMBL10046739 | 0.84 | LGALS1 (0.55) | LGALS1CYP1A2CYP2D6CYP2C19POLB | |
| SCHEMBL14213241 | 0.84 | LGALS1 (0.54) | LGALS1CYP1A2CYP2D6CYP2C19POLB | |
| SCHEMBL14193731 | 0.83 | KMT2A (0.58) | NPSR1HSD17B10TSHRHPGD | |
| SCHEMBL13992476 | 0.82 | LGALS1 (0.63) | LGALS1CYP1A2CYP2D6CYP2C19POLB | |
| SCHEMBL13992489 | 0.80 | LGALS1 (0.55) | LGALS1CYP1A2CYP2D6CYP2C19POLB | |
| SCHEMBL14213225 | 0.77 | CYP1A2 (0.52) | LGALS1CYP1A2CYP2D6CYP2C19POLB | |
| SCHEMBL14213209 | 0.77 | CYP1A2 (0.57) | LGALS1CYP1A2CYP2D6CYP2C19POLB | |
| SCHEMBL12986625 | 0.75 | ALDH1A1 (0.57) | LGALS1CYP1A2CYP2D6CYP2C19POLB | |
| SCHEMBL14213219 | 0.75 | CYP2D6 (0.55) | LGALS1CYP1A2CYP2D6CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120309801-A1 | CALIXARENE-BASED PEPTIDE CONFORMATION MIMETICS, METHODS OF USE, AND METHODS OF MAKING | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2012-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309801-A1 | CALIXARENE-BASED PEPTIDE CONFORMATION MIMETICS, METHODS OF USE, AND METHODS OF MAKING | CLSPN, BID, CALU | LGALS1 429/4885CYP1A2 4390/4885CYP2D6 4373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.