SCHEMBL1421334

SCHEMBL1421334

Ic1ccc2oc3ccc(I)cc3c2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 4/20 0.46
MAPT P10636 6/20 0.41
SMN1; SMN2 Q16637 5/20 0.41
AHR P35869 5/20 0.41
NPC1 O15118 4/20 0.41
KDM4E B2RXH2 4/20 0.41
ALDH1A1 P00352 4/20 0.41
RAB9A P51151 3/20 0.41
HPGD P15428 3/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
GFER P55789 1/20 0.38
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
HSD17B10 Q99714 2/20 0.33
PIM1 P11309 2/20 0.33
CSNK2A1 P68400 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22505850 0.91 MAPT (0.43) APPMAPTSMN1; SMN2AHRNPC1
SCHEMBL2549311 0.89 MAPT (0.59) APPMAPTSMN1; SMN2AHRNPC1
SCHEMBL2253956 0.87 PIM1 (0.46) APPMAPTSMN1; SMN2AHRNPC1
SCHEMBL19141521 0.87 NPC1 (0.62) APPMAPTSMN1; SMN2AHRNPC1
SCHEMBL13783172 0.87 MAPT (0.42) APPMAPTSMN1; SMN2NPC1KDM4E
SCHEMBL13911864 0.85 NPC1 (0.57) APPMAPTSMN1; SMN2NPC1KDM4E
SCHEMBL19719397 0.85 AHR (0.44) APPMAPTSMN1; SMN2AHRNPC1
SCHEMBL22133388 0.83 KDM4E (0.40) APPMAPTSMN1; SMN2AHRNPC1
SCHEMBL23658447 0.82 AHR (0.61) AHRALDH1A1KMT2ALMNA
SCHEMBL18820600 0.82 PIM1 (0.39) APPMAPTSMN1; SMN2AHRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530705-A1 Method for producing polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP claimed
EP-0530707-A1 Method for preparing polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP claimed
EP-0530703-A2 Method for the preparation of polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP claimed
EP-0522469-A2 Preparation of poly(benz(ox, imid, thi)azole) polymers EASTMAN KODAK COMPANY (US) 1993-01-13 EP claimed
US-5149755-A Aroatmic amine and halide reactants EASTMAN KODAK COMPANY (US) 1992-09-22 US claimed
US-12538704-B2 4H-imidazo[1,2-a]imidazoles for electronic applications UDC IRELAND LIMITED (IE) 2026-01-27 US disclosed
US-11991927-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-05-21 US disclosed
US-11991927-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-05-21 US disclosed
US-11839140-B2 Metal complexes comprising diazabenzmidazolocarbene ligands and the use thereof in OLEDS UDC IRELAND LIMITED (IE) 2023-12-05 US disclosed
CN-108117543-B Novel compound and organic electroluminescent device comprising the same 东进世美肯株式会社 2023-09-12 CN disclosed
US-20230090208-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications UDC IRELAND LTD (IE) 2023-03-23 US disclosed
US-20230026258-A1 Metal Complexes Comprising Diazabenzmidazolocarbene Ligands and the Use Thereof in OLEDS UDC IRELAND LTD (IE) 2023-01-26 US disclosed
US-20040048179-A1 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2004-03-11 US disclosed
EP-1394618-A2 Electrophotographic Photosensitive Member, Process Cartridge and Electrophotographic Apparatus CANON KABUSHIKI KAISHA (JP) 2004-03-03 EP disclosed
EP-0530705-A1 Method for producing polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP disclosed
EP-0530707-A1 Method for preparing polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP disclosed
EP-0530703-A2 Method for the preparation of polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP disclosed
EP-0522469-A2 Preparation of poly(benz(ox, imid, thi)azole) polymers EASTMAN KODAK COMPANY (US) 1993-01-13 EP disclosed
US-5149755-A Aroatmic amine and halide reactants EASTMAN KODAK COMPANY (US) 1992-09-22 US disclosed
US-4567280-A NITROGEN DIOXIDE; BY-PRODUCT INHIBITION UBE INDUSTRIES, LTD. (JP) 1986-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12538704-B2 4H-imidazo[1,2-a]imidazoles for electronic applications RIF1, NR2E1, NR3C1 APP 4474/4885MAPT 4314/4885SMN1; SMN2 2169/4885
US-20230090208-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications PAH, NISCH, KCNH1 APP 4302/4885MAPT 1665/4885SMN1; SMN2 3524/4885
US-20230026258-A1 Metal Complexes Comprising Diazabenzmidazolocarbene Ligands and the Use Thereof in OLEDS OCIAD1, OCIAD2, DRD2 APP 1617/4885MAPT 893/4885SMN1; SMN2 3047/4885
US-11839140-B2 Metal complexes comprising diazabenzmidazolocarbene ligands and the use thereof in OLEDS OCIAD1, OCIAD2, DRD2 APP 1617/4885MAPT 893/4885SMN1; SMN2 3047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.