Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14213890 | 0.88 | CNR1 (0.34) | CNR2 | |
| SCHEMBL14182801 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KDM4ETP53HPGDGRM2 | |
| SCHEMBL14213363 | 0.86 | GRM4 (0.37) | KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL14182805 | 0.82 | ALDH1A1 (0.42) | ALDH1A1KDM4ETP53HPGDGRM2 | |
| SCHEMBL14182807 | 0.81 | ALDH1A1 (0.41) | ALDH1A1KDM4ETP53HPGDGRM2 | |
| SCHEMBL14182803 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KDM4ETP53HPGDGRM2 | |
| SCHEMBL14182804 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KDM4ETP53HPGDGRM2 | |
| SCHEMBL14183003 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KDM4ETP53HPGDGRM2 | |
| SCHEMBL14182786 | 0.79 | ITK (0.47) | ALDH1A1KDM4ETP53HPGDSMN1; SMN2 | |
| SCHEMBL14213889 | 0.79 | ITK (0.40) | ALDH1A1KDM4ETP53HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |