Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 13/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182796 | 0.87 | RAB9A (0.44) | GRM4RAB9AKDM4EMAPTAGTR1 | |
| SCHEMBL14213699 | 0.86 | ALDH1A1 (0.39) | RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL14213890 | 0.83 | CNR1 (0.34) | — | |
| SCHEMBL14182800 | 0.83 | RAB9A (0.38) | GRM4RAB9AKDM4EMAPTAGTR1 | |
| SCHEMBL14182802 | 0.79 | ALDH1A1 (0.46) | RAB9AKDM4EMAPTAGTR1OPRK1 | |
| SCHEMBL14182794 | 0.79 | KDR (0.46) | GRM4RAB9AKDM4EKDR | |
| SCHEMBL14182799 | 0.78 | GRM4 (0.40) | GRM4RAB9AKDM4EKDREGFR | |
| SCHEMBL14182795 | 0.78 | GRM4 (0.48) | GRM4RAB9AKDM4EMAPTKMT2A | |
| SCHEMBL14182798 | 0.78 | GRM4 (0.48) | GRM4RAB9AKDM4EMAPTKMT2A | |
| SCHEMBL14183000 | 0.77 | RAB9A (0.52) | GRM4RAB9AKDM4EMAPTAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |