Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | ITK | Q08881 | 3/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14213699 | 0.88 | ALDH1A1 (0.39) | CNR2 | |
| SCHEMBL14182809 | 0.86 | CNR1 (0.36) | CNR1CNR2ITKSLC2A1MAOA | |
| SCHEMBL14213363 | 0.83 | GRM4 (0.37) | — | |
| SCHEMBL14182811 | 0.81 | CNR1 (0.41) | CNR1CNR2ITKSLC2A1MAOA | |
| SCHEMBL14213889 | 0.81 | ITK (0.40) | ITKSLC2A1MAOAMAOB | |
| SCHEMBL14183011 | 0.80 | ALDH1A1 (0.43) | CNR1CNR2ITKSLC2A1 | |
| SCHEMBL14183010 | 0.79 | ITK (0.45) | CNR1CNR2ITKSLC2A1MAOA | |
| SCHEMBL14182806 | 0.79 | ITK (0.44) | CNR1CNR2ITKSLC2A1MAOA | |
| SCHEMBL14182807 | 0.79 | ALDH1A1 (0.41) | CNR2ITK | |
| SCHEMBL14182786 | 0.78 | ITK (0.47) | ITKSLC2A1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |