Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4877431 | 0.80 | MAPT (0.69) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL4877424 | 0.80 | MAPT (0.69) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL20549105 | 0.75 | RAB9A (0.68) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL6285948 | 0.72 | RAB9A (0.66) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL6285944 | 0.72 | RAB9A (0.66) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL11066176 | 0.72 | ALDH1A1 (0.63) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL23539268 | 0.72 | GAA (0.47) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL16115787 | 0.72 | GAA (0.47) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL16115788 | 0.72 | GAA (0.47) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL359987 | 0.71 | SMN1; SMN2 (0.53) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |