SCHEMBL1421482

SCHEMBL1421482

CCOc1cc(C=C2SC(=S)N(c3ccc(F)cc3)C2=O)ccc1O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.73
MEN1 O00255 12/20 0.68
KMT2A Q03164 12/20 0.68
MAPT P10636 7/20 0.68
POLB P06746 4/20 0.62
IDE P14735 2/20 0.62
LMNA P02545 1/20 0.62
HTT P42858 1/20 0.62
GAA P10253 3/20 0.61
FABP4 P15090 1/20 0.61
ALDH1A1 P00352 2/20 0.60
NPSR1 Q6W5P4 2/20 0.60
NPC1 O15118 1/20 0.60
THRB P10828 1/20 0.60
ALOX12 P18054 1/20 0.60
RECQL P46063 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
MCL1 Q07820 1/20 0.60
HSPD1 P10809 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1421478 1.00 FAAH (0.73) FAAHMEN1KMT2AMAPTPOLB
SCHEMBL1421307 0.92 FAAH (0.62) FAAHMEN1KMT2AMAPTPOLB
SCHEMBL1421306 0.92 FAAH (0.62) FAAHMEN1KMT2AMAPTPOLB
SCHEMBL1421308 0.92 FAAH (0.62) FAAHMEN1KMT2AMAPTPOLB
SCHEMBL12726855 0.91 MEN1 (0.70) FAAHMEN1KMT2AMAPTPOLB
SCHEMBL1421492 0.90 MEN1 (0.68) FAAHMEN1KMT2AMAPTPOLB
SCHEMBL20005793 0.90 MEN1 (0.68) FAAHMEN1KMT2AMAPTPOLB
SCHEMBL1421490 0.90 MEN1 (0.68) FAAHMEN1KMT2AMAPTPOLB
SCHEMBL18103076 0.90 MEN1 (0.68) FAAHMEN1KMT2AMAPTPOLB
SCHEMBL1641528 0.90 MEN1 (0.84) FAAHMEN1KMT2AMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110098323-A1 INHIBITORS OF BACTERIAL BIOFILM FORMATION MICROBIOTIX, INC. (US) 2011-04-28 US disclosed
EP-2296476-A1 INHIBITORS OF BACTERIAL BIOFILM FORMATION Microbiotix, Inc. (US) 2011-03-23 EP disclosed
WO-2009142720-A1 INHIBITORS OF BACTERIAL BIOFILM FORMATION MICROBIOTIX, INC. (US) 2009-11-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110098323-A1 INHIBITORS OF BACTERIAL BIOFILM FORMATION BLVRB, TFPI, FOSB FAAH 2242/4885MEN1 4836/4885KMT2A 3896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.