Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 13/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3108919 | 0.94 | LMNA (0.51) | LMNAPOLBSTING1GAAIRAK4 | |
| SCHEMBL12798723 | 0.85 | LMNA (0.52) | LMNAPOLBSTING1GAAIRAK4 | |
| SCHEMBL3117837 | 0.85 | LMNA (0.52) | LMNAPOLBSTING1GAAIRAK4 | |
| SCHEMBL7457962 | 0.81 | LMNA (0.55) | LMNAPOLBSTING1GAAIRAK4 | |
| SCHEMBL14185462 | 0.81 | LMNA (0.59) | LMNAPOLBSTING1GAAIRAK4 | |
| Penthiopyrad SCHEMBL14364841 | 0.80 | LMNA (0.51) | LMNAPOLBSTING1GAAIRAK4 | |
| Penthiopyrad SCHEMBL14364842 | 0.80 | LMNA (0.51) | LMNAPOLBSTING1GAAIRAK4 | |
| Penthiopyrad SCHEMBL18701 | 0.80 | LMNA (0.51) | LMNAPOLBSTING1GAAIRAK4 | |
| SCHEMBL24736516 | 0.78 | LMNA (0.52) | LMNAPOLBSTING1GAAIRAK4 | |
| SCHEMBL3114583 | 0.78 | IRAK4 (0.42) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113979-A1 | Fungicidal Mixtures of Thiophene Derivative | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113979-A1 | Fungicidal Mixtures of Thiophene Derivative | MRM1, CYP11A1, CYP11B1 | LMNA 3537/4885POLB 1716/4885STING1 2507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.