Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14113058 | 0.86 | CYP1A1 (0.44) | CYP1A1CYP1A2CYP1B1RAB9ANPC1 | |
| SCHEMBL14113059 | 0.81 | KDM4E (0.44) | CYP1A1CYP1A2CYP1B1RAB9ANPC1 | |
| SCHEMBL9507430 | 0.78 | NPC1 (0.48) | CYP1A1CYP1A2CYP1B1RAB9ANPC1 | |
| SCHEMBL9507434 | 0.78 | NPC1 (0.48) | CYP1A1CYP1A2CYP1B1RAB9ANPC1 | |
| SCHEMBL9724840 | 0.76 | CYP11B2 (0.65) | CYP1A1CYP1A2CYP1B1RAB9ANPC1 | |
| SCHEMBL9724843 | 0.76 | CYP11B2 (0.65) | CYP1A1CYP1A2CYP1B1RAB9ANPC1 | |
| SCHEMBL9509602 | 0.75 | MAPT (0.59) | CYP1A1CYP1A2CYP1B1RAB9ANPC1 | |
| SCHEMBL9509599 | 0.75 | MAPT (0.59) | CYP1A1CYP1A2CYP1B1RAB9ANPC1 | |
| SCHEMBL29881470 | 0.72 | CYP11B1 (0.61) | RAB9ANPC1KDM4EPOLBCYP2D6 | |
| SCHEMBL457158 | 0.72 | CYP11B1 (0.61) | RAB9ANPC1KDM4EPOLBCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080103302-A1 | Compounds for treatment of inflammation, diabetes and related disorders | THERACOS, INC. (US) | 2008-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103302-A1 | Compounds for treatment of inflammation, diabetes and related disorders | CPS1, ABAT, IL6 | CYP1A1 4223/4885CYP1A2 3699/4885CYP1B1 3387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.