Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.65 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.65 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724843 | 1.00 | CYP11B2 (0.65) | CYP11B2CYP19A1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9509602 | 0.86 | MAPT (0.59) | CYP11B2CYP19A1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9509599 | 0.86 | MAPT (0.59) | CYP11B2CYP19A1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9507267 | 0.82 | KMT2A (0.55) | CYP11B2CYP19A1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9509587 | 0.82 | EPHX2 (0.45) | CYP11B2CYP19A1CYP1A1CYP1B1CYP3A4 | |
| SCHEMBL9509584 | 0.82 | EPHX2 (0.45) | CYP11B2CYP19A1CYP1A1CYP1B1CYP3A4 | |
| SCHEMBL9507274 | 0.82 | KMT2A (0.55) | CYP11B2CYP19A1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL7995907 | 0.82 | ALDH1A1 (0.54) | CYP11B2CYP19A1CYP1B1KMT2AMEN1 | |
| SCHEMBL566814 | 0.82 | ALDH1A1 (0.54) | CYP11B2CYP19A1CYP1B1KMT2AMEN1 | |
| SCHEMBL566813 | 0.82 | ALDH1A1 (0.54) | CYP11B2CYP19A1CYP1B1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162357-A | FUNGICIDAL AZOLYLMETHYLOXIRANES | BASF AKTIENGESELLSCHAFT (DE) | 1992-11-10 | — | — | US | disclosed |
| EP-0421125-A2 | Fungicidal azolylmethyloxiranes | BASF Aktiengesellschaft (DE) | 1991-04-10 | — | — | EP | disclosed |