Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7630857 | 0.80 | KDM4E (0.54) | MAPTCES1MAPK1HTTLMNA | |
| SCHEMBL10720268 | 0.78 | LMNA (0.60) | CES1MAPK1HTTLMNAGAA | |
| SCHEMBL16566898 | 0.78 | CES1 (0.50) | CES1MAPK1HTTLMNAGAA | |
| SCHEMBL6792736 | 0.78 | CES1 (0.50) | MAPTHDAC8CES1MAPK1HTT | |
| SCHEMBL29679621 | 0.78 | CES1 (0.50) | CES1MAPK1HTTLMNAGAA | |
| SCHEMBL9082912 | 0.78 | MAPT (0.56) | MAPTHDAC8MAPK1KDM4EHDAC6 | |
| SCHEMBL1791035 | 0.76 | ALDH1A1 (0.64) | MAPTHDAC8CES1MAPK1HTT | |
| SCHEMBL29668746 | 0.76 | CES1 (0.60) | MAPTCES1MAPK1HTTLMNA | |
| SCHEMBL361933 | 0.76 | CES1 (0.60) | MAPTCES1MAPK1HTTLMNA | |
| SCHEMBL13129171 | 0.75 | CES1 (0.47) | CES1MAPK1HTTLMNAPLA2G2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378154-B2 | Radiation transparent glass, polycarbonate, polyethylene terephthalate, acrylic, methyl cellulose or polycycloolefin substrate, a fluoropolymer layer containing and a rare earth metal compound, and a low refractive index layer; fluorescence; light amplification; improved efficiency; light emitting diodes | DAIKIN INDUSTRIES, LTD. (JP) | 2008-05-27 | — | — | US | disclosed |