SCHEMBL1421650

SCHEMBL1421650

N#Cc1cc(F)cc(C#N)c1

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL56741 0.94 GRM5 (0.43) GRM5
SCHEMBL4457929 0.92 GRM5 (0.56) GRM5
SCHEMBL16953079 0.87 GRM5 (0.41) GRM5
SCHEMBL16957989 0.87 GRM5 (0.41) GRM5
SCHEMBL2767750 0.87 GRM5 (0.41) GRM5
SCHEMBL13606452 0.86 GRM5 (0.53) GRM5
SCHEMBL4460258 0.83 GRM5 (0.50) GRM5
SCHEMBL60145 0.83 TTR (0.50)
SCHEMBL4474671 0.82 GRM5 (0.38) GRM5
SCHEMBL1652055 0.82 TTR (0.43) GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118496409-A Caliper [3] acridine polymer and preparation method and application thereof 中国科学院化学研究所 2024-08-16 CN claimed
CN-107814760-B Preparation method and application of metal organic cage-shaped compound for preparing aniline by catalytic reduction of nitrobenzene 大连理工大学 2020-07-24 CN claimed
US-20090130726-A1 PROCESS FOR CONVERTING AROMATIC HALO-SUBSTITUTED DINITRILES INTO HALO-SUBSTITUTED CYANOCARBOXYLIC ACIDS ASTRAZENECA AB (SE) 2009-05-21 US claimed
EP-1929026-A1 NEW PROCESS FOR CONVERTING AROMATIC HALO-SUBSTITUTED DINITRILES INTO HALO-SUBSTITUTED CYANOCARBOXYLIC ACIDS AstraZeneca AB (SE) 2008-06-11 EP claimed
WO-2007035161-A1 NEW PROCESS FOR CONVERTING AROMATIC HALO-SUBSTITUTED DINITRILES INTO HALO-SUBSTITUTED CYANOCARBOXYLIC ACIDS ASTRAZENECA AB (SE) 2007-03-29 WO claimed
CN-1125042-C Process for preparing 3-cyano-2, 4-dihalogen-5-fluorobenzoic acid BAYER AG (DE) 2003-10-22 CN claimed
CN-1265644-A Method for preparing 3-cyano-2,4-dihalogen-5-flour-benzoic acid BAYER AG (DE) 2000-09-06 CN claimed
US-12364160-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2025-07-15 US disclosed
US-12274168-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic appliance IDEMITSU KOSAN CO., LTD. (JP) 2025-04-08 US disclosed
WO-2025031396-A1 SUBSTITUTED BENZOCYCLOBUTENE COMPOUND AND USES THEREOF IN THE FIELD OF MEDICINE 杭州安道药业有限公司 2025-02-13 WO disclosed
CN-118496409-A Caliper [3] acridine polymer and preparation method and application thereof 中国科学院化学研究所 2024-08-16 CN disclosed
WO-2024110668-A2 LIGANDS FOR METAL ORGANIC FRAMEWORKS AND A CATALYST-FREE METHOD OF MAKING SUCH ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2024-05-30 WO disclosed
CN-117712487-B Electrolyte, battery and power utilization system 深圳海辰储能科技有限公司 2024-04-16 CN disclosed
EP-0899256-A2 Method for production of organic fluorine compound NIPPON SHOKUBAI CO., LTD. (JP) 1999-03-03 EP disclosed
EP-0307897-B1 TRIFLUOROBENZENE COMPOUNDS AND PROCESS FOR PRODUCING THE SAME SDS Biotech K.K. (JP) 1993-03-17 EP disclosed
US-5068411-A Hydrolysis of 2,4,5-trifluoroisophthalonitrile in the presence of sulfuric acid to form 2,4,5-trifluoroisophthalic acid SDS BIOTECH K.K. (JP) 1991-11-26 US disclosed
US-5021605-A Chemical intermediates SDS BIOTECH K.K. (JP) 1991-06-04 US disclosed
EP-0307897-A1 Trifluorobenzene compounds and process for producing the same SDS Biotech K.K. (JP) 1989-03-22 EP disclosed
US-4684734-A Method for manufacture or organic fluorine compounds NIPPON SHOKUBAI KK CO., LTD. (JP) 1987-08-04 US disclosed
EP-0120575-A1 Organic fluorine compounds Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1984-10-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12274168-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic appliance MLX, H1-0, RER1 GRM5 3002/4885
US-12364160-B2 Organic electroluminescent element and electronic device RPL21, RPS21, RPL19 GRM5 3505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.