SCHEMBL56741

SCHEMBL56741

N#Cc1cc(F)cc(F)c1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 2/20 0.43
MEN1 O00255 1/20 0.40
TTR P02766 1/20 0.40
ALB P02768 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1421650 0.94 GRM5 (0.47) GRM5
SCHEMBL13606452 0.86 GRM5 (0.53) GRM5
SCHEMBL4457929 0.86 GRM5 (0.56) GRM5
Benzonitrile SCHEMBL28071141 0.85 TSHR (0.64) GRM5
SCHEMBL16957989 0.82 GRM5 (0.41) GRM5
SCHEMBL546136 0.82 GRM5 (0.43) GRM5
SCHEMBL19865421 0.82 TRPV4 (0.48) GRM5
SCHEMBL508381 0.82 CA12 (0.55) GRM5MEN1TTRALBKMT2A
SCHEMBL7873304 0.82 GRM5 (0.38) GRM5
SCHEMBL4474671 0.82 GRM5 (0.38) GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 826 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743438-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2026-05-20 EP claimed
US-20260005305-A1 BATTERY ZHUHAI COSMX BATTERY CO., LTD. (CN) 2026-01-01 US claimed
EP-4665705-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2025-12-24 EP claimed
WO-2025068995-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2025-04-03 WO claimed
CN-119650843-A Electrolyte and lithium ion battery 珠海冠宇电池股份有限公司 2025-03-18 CN claimed
CN-118970173-A Electrolyte and application thereof 珠海冠宇电池股份有限公司 2024-11-15 CN claimed
CN-118867398-A Battery cell 珠海冠宇电池股份有限公司 2024-10-29 CN claimed
WO-2024171098-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2024-08-22 WO claimed
CN-118440314-A Long comb-shaped ion string block-containing polyaryl ether nitrile ketone anion exchange membrane and preparation method thereof 华侨大学 2024-08-06 CN claimed
CN-118240200-A Low-dielectric fluorine-containing polyarylether resin and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2024-06-25 CN claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
EP-2611296-A2 FUNGICIDAL PYRAZOLES AND THEIR MIXTURES E.I. Du Pont De Nemours And Company (US) 2013-07-10 EP claimed
WO-2012031061-A2 FUNGICIDAL PYRAZOLES AND THEIR MIXTURES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-03-08 WO claimed
US-20110207000-A1 Nitrile additive for non-aqueous electrolyte rechargeable electrochemical cells UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY, THE 2011-08-25 US claimed
WO-2011056463-A2 FUNGICIDAL MIXTURES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-05-12 WO claimed
CN-1800168-A 5-n-propyl-2-(3,5-difluophenyl)pyridine preparation method UNIV TONGJI (CN) 2006-07-12 CN claimed
US-20040110990-A1 Catalytic reduction of nitriles to aldehydes LANXESS DEUTSCHLAND GMBH (DE) 2004-06-10 US claimed
CN-1483712-A Catalytic reduction method of benzonitrile to benzoaldehyde 2004-03-24 CN claimed
EP-1389608-A1 Catalytic reduction of benzonitrile derivatives to benzoaldehyde derivatives Bayer Chemicals AG (DE) 2004-02-18 EP claimed
EP-0284375-A1 Dopamine-beta-hydroxylase inhibitors SMITHKLINE BEECHAM CORPORATION (US) 1988-09-28 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260005305-A1 BATTERY CACNA1S, CACNA1D, CACNB1 GRM5 3586/4885MEN1 1564/4885TTR 4563/4885
US-20040110990-A1 Catalytic reduction of nitriles to aldehydes CAT, NIT2, IDH1 GRM5 3333/4885MEN1 1434/4885TTR 1073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.