Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13923990 | 0.90 | HDAC1 (0.33) | HDAC1HDAC4HDAC8ITGB3ITGA2B | |
| SCHEMBL6124828 | 0.88 | HDAC1 (0.35) | HDAC1HDAC4HDAC8ITGB3ITGA2B | |
| SCHEMBL7941871 | 0.88 | HDAC1 (0.35) | HDAC1HDAC4HDAC8ITGB3ITGA2B | |
| SCHEMBL8195602 | 0.84 | ITGB3 (0.37) | HDAC1HDAC4HDAC8ITGB3ITGA2B | |
| SCHEMBL8203250 | 0.84 | F2 (0.41) | HDAC1HDAC4ITGB3ITGA2B | |
| SCHEMBL8172094 | 0.80 | ELANE (0.32) | ITGB3ITGA2B | |
| SCHEMBL6124822 | 0.79 | F2 (0.33) | ITGB3ITGA2B | |
| SCHEMBL15580101 | 0.79 | ITGB3 (0.33) | HDAC1HDAC4HDAC8ITGB3ITGA2B | |
| SCHEMBL15501094 | 0.78 | HDAC1 (0.34) | HDAC1HDAC4HDAC8ITGB3ITGA2B | |
| SCHEMBL13071444 | 0.78 | ITGB3 (0.37) | HDAC1HDAC4HDAC8ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057873-A2 | INHIBITORS OF HEPATITIS C VIRUS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-15 | — | — | WO | disclosed |