Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086920 | 0.88 | KDM4E (0.59) | MAPK1KMT2AMEN1HPGDKDM4E | |
| SCHEMBL11010057 | 0.85 | ALDH1A1 (0.56) | MAPK1KMT2AMEN1HPGDKDM4E | |
| SCHEMBL5875315 | 0.83 | ABL1 (0.62) | KMT2AMEN1HPGDKDM4EALDH1A1 | |
| SCHEMBL28057743 | 0.83 | CA12 (0.49) | MAPK1KMT2AMEN1HPGDKDM4E | |
| SCHEMBL11815650 | 0.83 | CA12 (0.54) | KMT2AMEN1HPGDKDM4EALDH1A1 | |
| SCHEMBL9573768 | 0.82 | KMT2A (0.51) | MAPK1KMT2AMEN1HPGDKDM4E | |
| SCHEMBL235046 | 0.82 | TSHR (0.60) | MAPK1KMT2AKDM4EALDH1A1CA12 | |
| SCHEMBL3456352 | 0.81 | KDM4E (0.52) | MAPK1KMT2AMEN1HPGDKDM4E | |
| SCHEMBL522136 | 0.80 | KMT2A (0.59) | MAPK1KMT2AHPGDKDM4EALDH1A1 | |
| SCHEMBL5248889 | 0.80 | MAPK1 (0.54) | MAPK1KMT2AKDM4EALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008051757-A1 | COMPOSITIONS AND METHODS FOR MODULATING C-KIT AND PDGFR RECEPTORS | IRM LLC (BM) | 2008-05-02 | — | — | WO | disclosed |