SCHEMBL235046

SCHEMBL235046

CCOC(=O)c1ccc(Cl)cc1C(=O)OCC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.60
MAPK1 P28482 1/20 0.55
CA12 O43570 2/20 0.54
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
CA7 P43166 2/20 0.54
CA9 Q16790 2/20 0.54
CA14 Q9ULX7 2/20 0.54
ALOX15 P16050 2/20 0.53
CYP4F2 P78329 1/20 0.51
CYP4A11 Q02928 1/20 0.51
KDM4E B2RXH2 4/20 0.51
KMT2A Q03164 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.49
MAOB P27338 1/20 0.49
HSD17B10 Q99714 2/20 0.48
MAPT P10636 1/20 0.48
HTT P42858 1/20 0.48
BAZ2B Q9UIF8 1/20 0.47
BAZ2A Q9UIF9 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31268668 0.91 MAPK1 (0.51) TSHRMAPK1CA12CA1CA2
SCHEMBL4625784 0.89 TSHR (0.57) TSHRMAPK1CA12CA1CA2
SCHEMBL4626740 0.89 TSHR (0.59) TSHRMAPK1CA12CA1CA2
SCHEMBL4628279 0.89 TSHR (0.49) TSHRMAPK1CA12CA1CA2
SCHEMBL4628005 0.89 TSHR (0.49) TSHRMAPK1CA12CA1CA2
SCHEMBL11225504 0.87 CYP4F2 (0.67) TSHRMAPK1ALOX15CYP4F2CYP4A11
SCHEMBL549144 0.87 MAPK1 (0.54) TSHRMAPK1CA12CA1CA2
SCHEMBL5248889 0.87 MAPK1 (0.54) TSHRMAPK1CA12CA1CA2
SCHEMBL522136 0.87 KMT2A (0.59) TSHRMAPK1CA12CA1CA2
SCHEMBL3304119 0.86 CA12 (0.70) TSHRMAPK1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0363922-B1 The process for the preparation of 3,3',4,4'-biphenyltetracarboxylic acid and its derivatives CHANGCHUN APPLIED CHEMISTRY (CN) 1996-04-10 EP claimed
US-5081281-A Process for the preparation of 3,3',4,4'-biphenyltetracarboxylic acid and its derivatives CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY (CN) 1992-01-14 US claimed
EP-0363922-A2 The process for the preparation of 3,3',4,4'-biphenyltetracarboxylic acid and its derivatives CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY (CN) 1990-04-18 EP claimed
US-12060378-B2 Solid catalyst component for olefin polymerization, method for producing solid catalyst component for olefin polymerization, method for producing catalyst for olefin polymerization and method for producing polymer of olefin TOHO TITANIUM CO., LTD. (JP) 2024-08-13 US disclosed
US-20240218087-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, METHOD FOR PRODUCING POLYMER OF OLEFIN, POLYMER OF OLEFIN, METHOD FOR PRODUCING PROPYLENE-BASED BLOCK COPOLYMER, AND PROPYLENE-BASED BLOCK COPOLYMER TOHO TITANIUM CO., LTD. (JP) 2024-07-04 US disclosed
EP-4349874-A1 OLEFIN POLYMERIZATION SOLID CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, MANUFACTURING METHOD FOR OLEFIN POLYMER, OLEFIN POLYMER, MANUFACTURING METHOD FOR PROPYLENE-BASED BLOCK COPOLYMER, AND PROPYLENE-BASED BLOCK COPOLYMER TOHO TITANIUM CO., LTD. (JP) 2024-04-10 EP disclosed
CN-117425682-A Solid catalyst component for olefin polymerization, catalyst for olefin polymerization, process for producing olefin polymer, process for producing propylene block copolymer, and propylene block copolymer 东邦钛株式会社 2024-01-19 CN disclosed
CN-115894416-A Method for selectively preparing 2, 3',4' -biphenyl tetracarboxylic dianhydride 大连新阳光材料科技有限公司 2023-04-04 CN disclosed
CN-115867395-A Method for producing Mg-containing particles 东邦钛株式会社 2023-03-28 CN disclosed
US-20220372052-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING CATALYST FOR OLEFIN POLYMERIZATION AND METHOD FOR PRODUCING POLYMER OF OLEFIN TOHO TITANIUM CO., LTD. (JP) 2022-11-24 US disclosed
CN-115246895-A Solid catalyst component for olefin polymerization, process for producing the same, process for producing catalyst for olefin polymerization, and process for producing olefin polymer 东邦钛株式会社 2022-10-28 CN disclosed
CN-1410598-A Preparation of biphenylyl tetra formicdianhydride and its derivative using electrochemical method CHANGCHUN APPLIED CHEMISTRY (CN) 2003-04-16 CN disclosed
US-20030036594-A1 Phthalic diester derivatives and electron donors TOHO TITANIUM CO., LTD. (JP) 2003-02-20 US disclosed
EP-1283222-A1 SOLID CATALYST INGREDIENT AND CATALYST EACH FOR OLEFIN POLYMERIZATION AND PROPYLENE BLOCK COPOLYMER Toho Catalyst Co., Ltd. (JP) 2003-02-12 EP disclosed
EP-1209172-A1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2002-05-29 EP disclosed
EP-1188739-A1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO., LTD. (JP) 2002-03-20 EP disclosed
US-4628126-A Process for the production of dihydroxybenzenes DEGUSSA AKTIENGESELLSCHAFT (DE) 1986-12-09 US disclosed
US-4564514-A Process for the production of water-free organic hydrogen peroxide solution DEGUSSA AKTIENGESELLSCHAFT (DE) 1986-01-14 US disclosed
US-4551562-A Process for the production of dihydroxybenzenes DEGUSSA AKTIENGESELLSCHAFT (DE) 1985-11-05 US disclosed
US-4025505-A ANTICONVULSANTS CIBA-GEIGY CORPORATION (US) 1977-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220372052-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING CATALYST FOR OLEFIN POLYMERIZATION AND METHOD FOR PRODUCING POLYMER OF OLEFIN EEF2, ELL, POF1B TSHR 3311/4885MAPK1 2011/4885CA12 524/4885
US-12060378-B2 Solid catalyst component for olefin polymerization, method for producing solid catalyst component for olefin polymerization, method for producing catalyst for olefin polymerization and method for producing polymer of olefin EEF2, ELL, POF1B TSHR 3311/4885MAPK1 2011/4885CA12 524/4885
US-20030036594-A1 Phthalic diester derivatives and electron donors HPD, ETFA, PPOX TSHR 4817/4885MAPK1 921/4885CA12 2609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.